Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 3/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.47 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.47 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | BLM | P54132 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.31 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.31 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.31 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19064688 | 1.00 | CYP1A2 (0.47) | CYP1A2ALOX15GRM2GRM3CYP2D6 | |
| SCHEMBL17423089 | 1.00 | CYP1A2 (0.47) | CYP1A2ALOX15GRM2GRM3CYP2D6 | |
| Hydrochloric Acid SCHEMBL19064832 | 0.98 | CYP1A2 (0.46) | CYP1A2ALOX15GRM2GRM3CYP2D6 | |
| SCHEMBL9132272 | 0.81 | CYP1A2 (0.47) | CYP1A2ALOX15GRM2GRM3CYP2D6 | |
| SCHEMBL10993356 | 0.81 | CYP1A2 (0.47) | CYP1A2ALOX15GRM2GRM3CYP2D6 | |
| Hydrochloric Acid SCHEMBL25335642 | 0.80 | CYP1A2 (0.36) | CYP1A2ALOX15GRM2GRM3CYP2D6 | |
| Hydrochloric Acid SCHEMBL30484614 | 0.80 | CYP1A2 (0.36) | CYP1A2ALOX15GRM2GRM3CYP2D6 | |
| SCHEMBL3550569 | 0.79 | BACE1 (0.41) | KMT2A | |
| SCHEMBL3550573 | 0.79 | BACE1 (0.41) | KMT2A | |
| Hydrochloric Acid SCHEMBL29035273 | 0.78 | BACE1 (0.40) | KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230055237-A1 | COMPOUNDS AND METHODS FOR THE TREATMENT OF CYSTIC FIBROSIS | FLATLEY DISCOVERY LAB, LLC | 2023-02-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230055237-A1 | COMPOUNDS AND METHODS FOR THE TREATMENT OF CYSTIC FIBROSIS | CFTR, MPST, CRAT | CYP1A2 634/4885ALOX15 1222/4885GRM2 4881/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.