Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNK2 | Q07912 | 12/20 | 0.49 |
| ▸ | HTR1A | P08908 | 2/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.41 |
| ▸ | LCK | P06239 | 2/20 | 0.41 |
| ▸ | SRC | P12931 | 2/20 | 0.41 |
| ▸ | TEK | Q02763 | 1/20 | 0.41 |
| ▸ | BTK | Q06187 | 2/20 | 0.39 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.39 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.39 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30289682 | 0.88 | TNK2 (0.43) | TNK2LCKSRCTEKMAPK14 | |
| SCHEMBL30289668 | 0.87 | TNK2 (0.38) | TNK2BTK | |
| SCHEMBL30289731 | 0.87 | TNK2 (0.39) | TNK2 | |
| SCHEMBL30289669 | 0.84 | TNK2 (0.38) | TNK2 | |
| SCHEMBL30289603 | 0.83 | TNK2 (0.38) | TNK2BTK | |
| SCHEMBL30289565 | 0.83 | TNK2 (0.38) | TNK2 | |
| SCHEMBL30289737 | 0.82 | BTK (0.38) | TNK2LCKSRCTEKBTK | |
| SCHEMBL30289648 | 0.81 | TNK2 (0.45) | TNK2BTK | |
| SCHEMBL30289644 | 0.80 | BTK (0.47) | TNK2BTK | |
| SCHEMBL30289663 | 0.79 | TNK2 (0.44) | TNK2LCKBTKMAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115894497-A | Imidazopyrimidine compounds, and preparation method and application thereof | 四川科伦博泰生物医药股份有限公司 | 2023-04-04 | — | — | CN | disclosed |