SCHEMBL30289669

SCHEMBL30289669

Nc1nccc2c(C3CC4CCC(C3)O4)nc(-c3ccc(Oc4ccccc4)cc3)n12

nearest known ligand 0.38

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
TNK2 Q07912 20/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30289697 0.84 TNK2 (0.49) TNK2
SCHEMBL30289682 0.84 TNK2 (0.43) TNK2
SCHEMBL30289731 0.83 TNK2 (0.39) TNK2
SCHEMBL30289565 0.82 TNK2 (0.38) TNK2
SCHEMBL30289603 0.82 TNK2 (0.38) TNK2
SCHEMBL30289737 0.81 BTK (0.38) TNK2
SCHEMBL30289668 0.80 TNK2 (0.38) TNK2
SCHEMBL30289648 0.78 TNK2 (0.45) TNK2
SCHEMBL30289677 0.76 SLC6A3 (0.42) TNK2
SCHEMBL30289663 0.75 TNK2 (0.44) TNK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115894497-A Imidazopyrimidine compounds, and preparation method and application thereof 四川科伦博泰生物医药股份有限公司 2023-04-04 CN disclosed