Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 14/20 | 0.69 |
| ▸ | CTSG | P08311 | 8/20 | 0.69 |
| ▸ | MAOA | P21397 | 4/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.62 |
| ▸ | MAPT | P10636 | 3/20 | 0.62 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.62 |
| ▸ | MAOB | P27338 | 2/20 | 0.62 |
| ▸ | TSHR | P16473 | 2/20 | 0.62 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.62 |
| ▸ | HPGD | P15428 | 2/20 | 0.62 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.62 |
| ▸ | LMNA | P02545 | 1/20 | 0.62 |
| ▸ | HTT | P42858 | 1/20 | 0.62 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.57 |
| ▸ | AURKA | O14965 | 1/20 | 0.51 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11297243 | 0.88 | ELANE (0.51) | ELANECTSGMAOAALDH1A1MAPT | |
| SCHEMBL11302517 | 0.83 | AURKA (0.54) | ELANECTSGMAOAALDH1A1MAPT | |
| SCHEMBL29109693 | 0.82 | ELANE (0.68) | ELANECTSGMAOAALDH1A1MAPT | |
| SCHEMBL9539603 | 0.81 | ELANE (0.74) | ELANECTSGALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL11236785 | 0.81 | ELANE (0.68) | ELANECTSGMAOAALDH1A1MAPT | |
| SCHEMBL29929513 | 0.80 | MAOA (0.77) | ELANECTSGMAOAALDH1A1MAPT | |
| SCHEMBL6901176 | 0.80 | MAOA (0.77) | ELANECTSGMAOAALDH1A1MAPT | |
| SCHEMBL8382640 | 0.80 | ELANE (0.78) | ELANECTSGMAOAALDH1A1MAPT | |
| Danthron SCHEMBL30544826 | 0.79 | MAPT (1.00) | ELANECTSGMAOAALDH1A1MAPT | |
| Danthron SCHEMBL29356886 | 0.79 | MAPT (1.00) | ELANECTSGMAOAALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112920141-B | Rhein derivatives and antiviral application thereof | 中检科医药科技(北京)集团有限公司 | 2023-03-17 | — | — | CN | disclosed |