Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | CES2 | O00748 | 2/20 | 0.42 |
| ▸ | THRB | P10828 | 3/20 | 0.41 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.39 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.39 |
| ▸ | THRA | P10827 | 1/20 | 0.38 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.38 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.38 |
| ▸ | FAAH | O00519 | 7/20 | 0.37 |
| ▸ | CES1 | P23141 | 5/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30294081 | 1.00 | TSHR (0.51) | TSHRHPGDALDH1A1CYP3A4TP53 | |
| SCHEMBL30294108 | 1.00 | TSHR (0.51) | TSHRHPGDALDH1A1CYP3A4TP53 | |
| SCHEMBL30294082 | 0.86 | TSHR (0.48) | TSHRHPGDALDH1A1CYP3A4TP53 | |
| SCHEMBL30294079 | 0.86 | TSHR (0.50) | TSHRHPGDALDH1A1CYP3A4TP53 | |
| SCHEMBL21392010 | 0.83 | TSHR (0.55) | TSHRHPGDALDH1A1CYP3A4TP53 | |
| SCHEMBL30294074 | 0.83 | TSHR (0.47) | TSHRHPGDALDH1A1CYP3A4TP53 | |
| SCHEMBL30294078 | 0.83 | TSHR (0.51) | TSHRHPGDALDH1A1CYP3A4TP53 | |
| SCHEMBL18737331 | 0.82 | TSHR (0.53) | TSHRHPGDALDH1A1CYP3A4TP53 | |
| SCHEMBL22420109 | 0.82 | TSHR (0.53) | TSHRHPGDALDH1A1CYP3A4TP53 | |
| SCHEMBL21166449 | 0.82 | TSHR (0.53) | TSHRHPGDALDH1A1CYP3A4TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4166580-A1 | FLUORINE-CONTAINING COMPOUND | Daikin Industries, Ltd. (JP) | 2023-04-19 | — | — | EP | disclosed |
| US-20230104378-A1 | FLUORINE-CONTAINING COMPOUND | DAIKIN INDUSTRIES, LTD. (JP) | 2023-04-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230104378-A1 | FLUORINE-CONTAINING COMPOUND | AFF1, AFF2, FXR1 | TSHR 1697/4885HPGD 4189/4885ALDH1A1 2656/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.