Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRL1 | P41146 | 4/20 | 0.55 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.55 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | ITGB2 | P05107 | 2/20 | 0.49 |
| ▸ | ICAM1 | P05362 | 2/20 | 0.49 |
| ▸ | ITGAL | P20701 | 2/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | ACE | P12821 | 4/20 | 0.48 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.47 |
| ▸ | ECE1 | P42892 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3369086 | 0.95 | OPRL1 (0.56) | OPRL1OPRM1POLBITGB2ICAM1 | |
| SCHEMBL2378435 | 0.91 | OPRL1 (0.66) | OPRL1OPRM1 | |
| Hydrochloric Acid SCHEMBL2378517 | 0.90 | OPRL1 (0.65) | OPRL1OPRM1 | |
| SCHEMBL2378945 | 0.88 | KMT2A (0.57) | OPRL1OPRM1TP53KMT2AMAPT | |
| SCHEMBL2380119 | 0.88 | KMT2A (0.57) | OPRL1OPRM1TP53KMT2AMAPT | |
| Potassium SCHEMBL2378910 | 0.87 | KMT2A (0.56) | OPRL1OPRM1TP53KMT2AMAPT | |
| SCHEMBL2378906 | 0.87 | KMT2A (0.56) | OPRL1OPRM1TP53KMT2AMAPT | |
| Potassium Ion SCHEMBL2379644 | 0.87 | OPRL1 (0.53) | OPRL1OPRM1ITGB2ICAM1ITGAL | |
| Hydrochloric Acid SCHEMBL302554 | 0.87 | KMT2A (0.56) | OPRL1OPRM1TP53KMT2AMAPT | |
| Hydrochloric Acid SCHEMBL2378939 | 0.87 | KMT2A (0.56) | OPRL1OPRM1TP53KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4852536-B2 | — | — | 2012-01-11 | — | — | JP | claimed |
| EP-1751093-A1 | SUBSTITUTED CYCLOHEXYLACETIC ACID DERIVATIVES | Grünenthal GmbH (DE) | 2007-02-14 | — | — | EP | claimed |
| WO-2005110976-A1 | SUBSTITUTED CYCLOHEXYLACETIC ACID DERIVATIVES | Grünenthal GmbH (DE) | 2005-11-24 | — | — | WO | claimed |