Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.57 |
| ▸ | MEN1 | O00255 | 3/20 | 0.57 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.57 |
| ▸ | OPRL1 | P41146 | 4/20 | 0.54 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.52 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
| ▸ | TACR1 | P25103 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2378945 | 1.00 | KMT2A (0.57) | KMT2AMEN1HCRTR1OPRL1OPRM1 | |
| SCHEMBL2378906 | 0.99 | KMT2A (0.56) | KMT2AMEN1HCRTR1OPRL1OPRM1 | |
| Hydrochloric Acid SCHEMBL302554 | 0.99 | KMT2A (0.56) | KMT2AMEN1HCRTR1OPRL1OPRM1 | |
| Potassium SCHEMBL2378910 | 0.99 | KMT2A (0.56) | KMT2AMEN1HCRTR1OPRL1OPRM1 | |
| Hydrochloric Acid SCHEMBL2378939 | 0.99 | KMT2A (0.56) | KMT2AMEN1HCRTR1OPRL1OPRM1 | |
| SCHEMBL3369086 | 0.93 | OPRL1 (0.56) | KMT2AMEN1OPRL1OPRM1MAPT | |
| Potassium Ion SCHEMBL2379644 | 0.90 | OPRL1 (0.53) | KMT2AMEN1HCRTR1OPRL1OPRM1 | |
| SCHEMBL2380008 | 0.88 | OPRL1 (0.56) | OPRL1OPRM1MAPTTACR1 | |
| SCHEMBL302945 | 0.88 | OPRL1 (0.55) | KMT2AOPRL1OPRM1MAPTTP53 | |
| Hydrochloric Acid SCHEMBL2379180 | 0.88 | OPRL1 (0.56) | OPRL1OPRM1MAPTTACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8017630-B2 | Cyclohexylacetic acid compounds | GRUENENTHAL GMBH (DE) | 2011-09-13 | — | — | US | claimed |
| EP-1751093-B1 | SUBSTITUTED CYCLOHEXYLACETIC ACID DERIVATIVES | GRUENENTHAL GMBH (DE) | 2010-10-06 | — | — | EP | claimed |
| US-20070129347-A1 | Cyclohexylacetic acid compounds | GRUENENTHAL GMBH (DE) | 2007-06-07 | — | — | US | claimed |
| US-8017630-B2 | Cyclohexylacetic acid compounds | GRUENENTHAL GMBH (DE) | 2011-09-13 | — | — | US | disclosed |
| EP-1751093-B1 | SUBSTITUTED CYCLOHEXYLACETIC ACID DERIVATIVES | GRUENENTHAL GMBH (DE) | 2010-10-06 | — | — | EP | disclosed |
| US-20070129347-A1 | Cyclohexylacetic acid compounds | GRUENENTHAL GMBH (DE) | 2007-06-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070129347-A1 | Cyclohexylacetic acid compounds | ACACA, HCAR2, PCCA | KMT2A 2621/4885MEN1 2416/4885HCRTR1 665/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.