Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 15/20 | 0.60 |
| ▸ | MTNR1B | P49286 | 14/20 | 0.60 |
| ▸ | NOTUM | Q6P988 | 3/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.60 |
| ▸ | NQO2 | P16083 | 3/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.60 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.60 |
| ▸ | HPGD | P15428 | 2/20 | 0.60 |
| ▸ | BLM | P54132 | 2/20 | 0.60 |
| ▸ | MEN1 | O00255 | 1/20 | 0.60 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.60 |
| ▸ | MPO | P05164 | 1/20 | 0.60 |
| ▸ | HTR1A | P08908 | 1/20 | 0.60 |
| ▸ | HTR2B | P41595 | 1/20 | 0.60 |
| ▸ | RAB9A | P51151 | 1/20 | 0.60 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.60 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30295239 | 1.00 | MTNR1A (0.60) | MTNR1AMTNR1BNOTUMCYP1A2ALDH1A1 | |
| SCHEMBL27085139 | 1.00 | MTNR1A (0.60) | MTNR1AMTNR1BNOTUMCYP1A2ALDH1A1 | |
| SCHEMBL25101135 | 1.00 | MTNR1A (0.60) | MTNR1AMTNR1BNOTUMCYP1A2ALDH1A1 | |
| SCHEMBL25101193 | 1.00 | MTNR1A (0.60) | MTNR1AMTNR1BNOTUMCYP1A2ALDH1A1 | |
| SCHEMBL27085124 | 0.93 | MTNR1A (0.60) | MTNR1AMTNR1BNOTUMCYP1A2ALDH1A1 | |
| SCHEMBL30630322 | 0.89 | MTNR1A (0.62) | MTNR1AMTNR1BNOTUMCYP1A2ALDH1A1 | |
| SCHEMBL27085225 | 0.89 | MTNR1A (0.62) | MTNR1AMTNR1BNOTUMCYP1A2ALDH1A1 | |
| SCHEMBL15902786 | 0.89 | HTR2A (0.56) | KDM4ECYP2D6MEN1MPOKMT2A | |
| SCHEMBL15902334 | 0.89 | HTR2A (0.56) | KDM4ECYP2D6MEN1MPOKMT2A | |
| SCHEMBL30295376 | 0.88 | MTNR1A (0.53) | MTNR1AMTNR1BNOTUMCYP1A2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4392037-A1 | THERAPEUTIC COMPOSITIONS AND RELATED METHODS | Boyce Thompson Institute for Plant Research Inc. (US) | 2024-07-03 | — | — | EP | disclosed |
| WO-2023028350-A1 | THERAPEUTIC COMPOSITIONS AND RELATED METHODS | BOYCE THOMPSON INSTITUTE FOR PLANT RESEARCH, INC. (US) | 2023-03-02 | — | — | WO | disclosed |