Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STK4 | Q13043 | 7/20 | 0.43 |
| ▸ | STK3 | Q13188 | 7/20 | 0.43 |
| ▸ | CNR1 | P21554 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.42 |
| ▸ | RET | P07949 | 6/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | LRRK2 | Q5S007 | 5/20 | 0.38 |
| ▸ | ADK | P55263 | 1/20 | 0.36 |
| ▸ | LIMK2 | P53671 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31301627 | 0.91 | STK4 (0.46) | STK4STK3CNR1CNR2LMNA | |
| SCHEMBL30295781 | 0.83 | STK4 (0.46) | STK4STK3LMNALRRK2ADK | |
| SCHEMBL30295744 | 0.82 | STK4 (0.41) | STK4STK3LMNALRRK2ADK | |
| SCHEMBL30295816 | 0.80 | LMNA (0.47) | STK4STK3LMNALRRK2ADK | |
| SCHEMBL30295809 | 0.80 | LMNA (0.46) | STK4STK3LMNALRRK2TP53 | |
| SCHEMBL30296050 | 0.80 | LRRK2 (0.62) | STK4STK3CNR2LMNALRRK2 | |
| SCHEMBL30295703 | 0.77 | STK4 (0.45) | STK4STK3LMNALRRK2TP53 | |
| SCHEMBL30295902 | 0.77 | STK4 (0.44) | STK4STK3LMNALRRK2TP53 | |
| SCHEMBL30295700 | 0.74 | SRC (0.42) | STK4STK3LMNALRRK2ADK | |
| SCHEMBL31034554 | 0.72 | CNR1 (0.35) | CNR1CNR2RET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023055731-A1 | INHIBITORS OF SERINE/THREONINE PROTEIN KINASE STK3 OR STK4 AND USES THEREOF | Sanford Burnham Prebys Medical Discovery Institute (US) | 2023-04-06 | — | — | WO | disclosed |