Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFE2L2 | Q16236 | 6/20 | 0.33 |
| ▸ | EDNRB | P24530 | 4/20 | 0.33 |
| ▸ | EDNRA | P25101 | 4/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24823033 | 0.89 | NFE2L2 (0.35) | NFE2L2EDNRBEDNRA | |
| SCHEMBL25084130 | 0.89 | TSHR (0.31) | NFE2L2EDNRA | |
| SCHEMBL25289959 | 0.86 | EDNRA (0.39) | NFE2L2EDNRBEDNRA | |
| SCHEMBL24822787 | 0.85 | NFE2L2 (0.34) | NFE2L2 | |
| SCHEMBL30743771 | 0.85 | NFE2L2 (0.34) | NFE2L2 | |
| SCHEMBL24823054 | 0.81 | NFE2L2 (0.35) | NFE2L2EDNRBEDNRA | |
| SCHEMBL30743748 | 0.80 | — | — | |
| SCHEMBL27207869 | 0.80 | — | — | |
| SCHEMBL31017548 | 0.80 | EDNRB (0.44) | EDNRBEDNRA | |
| SCHEMBL25180875 | 0.80 | EDNRA (0.36) | EDNRBEDNRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117836294-A | Biological antagonist containing aromatic ring, preparation method and application thereof | 上海翰森生物医药科技有限公司 | 2024-04-05 | — | — | CN | disclosed |
| WO-2023025277-A1 | AROMATIC RING-CONTAINING BIOLOGICAL ANTAGONIST, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 上海翰森生物医药科技有限公司 | 2023-03-02 | — | — | WO | disclosed |