Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT3 | P40763 | 1/20 | 0.38 |
| ▸ | PTGES2 | Q9H7Z7 | 3/20 | 0.36 |
| ▸ | KAT6A | Q92794 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4279787 | 0.82 | CA1 (0.38) | STAT3PTGES2CYP2C9SMN1; SMN2 | |
| SCHEMBL30295970 | 0.82 | CA1 (0.38) | STAT3PTGES2CYP2C9SMN1; SMN2 | |
| SCHEMBL30844567 | 0.82 | MEN1 (0.32) | KAT6ALMNACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL30296205 | 0.79 | CA1 (0.38) | STAT3PTGES2LMNACYP3A4CYP2C9 | |
| SCHEMBL30844579 | 0.71 | CA12 (0.33) | CYP2C9 | |
| SCHEMBL12874173 | 0.70 | IDO1 (0.57) | LMNAIDO1 | |
| SCHEMBL21796063 | 0.70 | TACR1 (0.38) | CYP2D6IDO1 | |
| SCHEMBL2874386 | 0.69 | MMP2 (0.39) | KAT6ACYP1A2CYP3A4CYP2D6CYP2C19 | |
| Hydrochloric Acid SCHEMBL5805298 | 0.69 | STAT3 (0.45) | STAT3PTGES2CYP2C9 | |
| SCHEMBL30296163 | 0.69 | CA1 (0.36) | STAT3PTGES2CYP2C9SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023025277-A1 | AROMATIC RING-CONTAINING BIOLOGICAL ANTAGONIST, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 上海翰森生物医药科技有限公司 | 2023-03-02 | — | — | WO | disclosed |