Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 6/20 | 0.44 |
| ▸ | KDM1B | Q8NB78 | 4/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2554312 | 1.00 | KDM1A (0.44) | KDM1AKDM1BNPC1RAB9AKCNH2 | |
| SCHEMBL17466054 | 0.92 | KDM1A (0.37) | KDM1AKDM1BNPC1RAB9A | |
| SCHEMBL3367070 | 0.83 | KDM1A (0.37) | KDM1AKDM1BKCNH2 | |
| SCHEMBL24697715 | 0.82 | KDM1A (0.36) | KDM1AKDM1BKCNH2 | |
| SCHEMBL3824032 | 0.82 | POLB (0.33) | KDM1AKDM1BNPC1RAB9A | |
| SCHEMBL30296659 | 0.81 | KDM1A (0.46) | KDM1AKDM1BNPC1RAB9AKCNH2 | |
| SCHEMBL364604 | 0.81 | KDM1A (0.46) | KDM1AKDM1BNPC1RAB9AKCNH2 | |
| SCHEMBL6301457 | 0.80 | GPR84 (0.37) | KDM1AKDM1BKCNH2 | |
| SCHEMBL856379 | 0.80 | KDM1A (0.39) | KDM1AKDM1BNPC1RAB9AKCNH2 | |
| SCHEMBL29976628 | 0.79 | KDM1A (0.49) | KDM1AKDM1BKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4702021-A1 | COMPOUNDS CAPABLE OF MODULATING GPR65 | Pathios Therapeutics Limited (GB) | 2026-03-04 | — | — | EP | disclosed |
| WO-2024224064-A1 | COMPOUNDS CAPABLE OF MODULATING GPR65 | Pathios Therapeutics Limited (GB) | 2024-10-31 | — | — | WO | disclosed |
| EP-4419203-A1 | TRICYCLIC GPR65 MODULATORS | Pathios Therapeutics Limited (GB) | 2024-08-28 | — | — | EP | disclosed |
| WO-2023067322-A1 | TRICYCLIC GPR65 MODULATORS | Pathios Therapeutics Limited (GB) | 2023-04-27 | — | — | WO | disclosed |