Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | PKLR | P30613 | 5/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | REV1 | Q9UBZ9 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3275353 | 0.90 | LMNA (0.53) | LMNAHTTSMN1; SMN2KMT2AHPGD | |
| SCHEMBL304091 | 0.83 | LMNA (0.56) | LMNAHTTSMN1; SMN2KMT2AHPGD | |
| SCHEMBL3275402 | 0.82 | LMNA (0.64) | LMNAHTTSMN1; SMN2KMT2AHPGD | |
| SCHEMBL303307 | 0.80 | LMNA (0.71) | LMNAHTTSMN1; SMN2KMT2AHPGD | |
| SCHEMBL302104 | 0.78 | LMNA (0.61) | LMNAHTTSMN1; SMN2KMT2AHPGD | |
| SCHEMBL1711049 | 0.78 | LMNA (0.62) | LMNAHTTSMN1; SMN2KMT2AHPGD | |
| SCHEMBL303551 | 0.78 | LMNA (0.60) | LMNAHTTSMN1; SMN2KMT2AHPGD | |
| SCHEMBL1710747 | 0.76 | LMNA (0.59) | LMNAHTTSMN1; SMN2KMT2AHPGD | |
| SCHEMBL303907 | 0.76 | LMNA (0.65) | LMNAHTTSMN1; SMN2KMT2AHPGD | |
| SCHEMBL302243 | 0.76 | LMNA (0.62) | LMNAHTTSMN1; SMN2KMT2AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2012500834-A | — | — | 2012-01-12 | — | — | JP | claimed |
| EP-2344456-A1 | NOVEL POTASSIUM CHANNEL BLOCKER | Xention Limited (GB) | 2011-07-20 | — | — | EP | claimed |
| WO-2010023445-A1 | NOVEL POTASSIUM CHANNEL BLOCKER | XENTION LIMITED (GB) | 2010-03-04 | — | — | WO | claimed |