Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.42 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.42 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.42 |
| ▸ | MINK1 | Q8N4C8 | 2/20 | 0.42 |
| ▸ | TNIK | Q9UKE5 | 2/20 | 0.42 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.42 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.41 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.40 |
| ▸ | NFATC1 | O95644 | 1/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.38 |
| ▸ | SYK | P43405 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26030813 | 0.84 | IDO1 (0.53) | IDO1MAPTDYRK1AMAP4K4MINK1 | |
| SCHEMBL22068158 | 0.83 | IDO1 (0.55) | IDO1MAPTDYRK1AMAP4K4MINK1 | |
| SCHEMBL6642380 | 0.77 | NOTUM (0.47) | CLK4DYRK1AMAPK1CYP2A6 | |
| SCHEMBL31472663 | 0.77 | NOTUM (0.48) | IDO1MAPTMAP4K4MINK1TNIK | |
| SCHEMBL21333215 | 0.77 | NOTUM (0.48) | IDO1MAPTMAP4K4MINK1TNIK | |
| SCHEMBL28155744 | 0.77 | IDO1 (0.51) | IDO1MAPTMAP4K4MINK1TNIK | |
| SCHEMBL15349904 | 0.74 | IDO1 (0.45) | IDO1MAP4K4MINK1TNIKLOXL2 | |
| SCHEMBL30062513 | 0.74 | IDO1 (0.45) | IDO1MAPTDYRK1AMAP4K4MINK1 | |
| SCHEMBL30427602 | 0.74 | ADORA2B (0.48) | IDO1MAPTMAP4K4MINK1TNIK | |
| SCHEMBL19995233 | 0.74 | IDO1 (0.45) | IDO1MAPTDYRK1AMAP4K4MINK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023040830-A1 | AHR INHIBITOR, USE THEREOF, AND PREPARATION METHOD THEREFOR | 北京华森英诺生物科技有限公司 | 2023-03-23 | — | — | WO | disclosed |