Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 10/20 | 0.72 |
| ▸ | RXRA | P19793 | 3/20 | 0.68 |
| ▸ | RXRB | P28702 | 3/20 | 0.68 |
| ▸ | RXRG | P48443 | 3/20 | 0.68 |
| ▸ | NPC1 | O15118 | 3/20 | 0.68 |
| ▸ | RAB9A | P51151 | 3/20 | 0.68 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.66 |
| ▸ | MAOA | P21397 | 2/20 | 0.64 |
| ▸ | MAOB | P27338 | 2/20 | 0.64 |
| ▸ | POLB | P06746 | 1/20 | 0.63 |
| ▸ | GFER | P55789 | 1/20 | 0.63 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.63 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.63 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.63 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.63 |
| ▸ | HRH1 | P35367 | 1/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.59 |
| ▸ | TP53 | P04637 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12472442 | 0.97 | HRH3 (0.72) | HRH3RXRARXRBRXRGNPC1 | |
| SCHEMBL17026485 | 0.87 | MAOA (0.61) | HRH3RXRARXRBRXRGNPC1 | |
| SCHEMBL3077665 | 0.85 | HRH3 (0.67) | HRH3RXRARXRBRXRGNPC1 | |
| SCHEMBL5450398 | 0.84 | HRH3 (1.00) | HRH3NPC1RAB9ACYP2D6HRH1 | |
| SCHEMBL13765599 | 0.84 | HRH3 (0.57) | HRH3RXRARXRBRXRGNPC1 | |
| SCHEMBL6420814 | 0.84 | MAOA (0.65) | HRH3RXRARXRBRXRGNPC1 | |
| SCHEMBL15818649 | 0.83 | MAOA (0.66) | HRH3RXRARXRBRXRGNPC1 | |
| SCHEMBL8462058 | 0.83 | RXRB (0.61) | HRH3RXRARXRBRXRGNPC1 | |
| Hydrochloric Acid SCHEMBL4937090 | 0.83 | HRH3 (0.97) | HRH3NPC1RAB9ACYP2D6HRH1 | |
| SCHEMBL6225615 | 0.83 | MAOB (0.63) | HRH3RXRARXRBRXRGNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119100936-A | In the ilast group Synthesis method of intermediate | 杭州诺澳生物医药科技有限公司 | 2024-12-10 | — | — | CN | disclosed |
| US-20230286917-A1 | HISTONE DEMETHYLASE INHIBITORS | CELGENE QUANTICEL RESEARCH, INC. (US) | 2023-09-14 | — | — | US | disclosed |
| US-11639333-B2 | Histone demethylase inhibitors | CELGENE QUANTICEL RESEARCH, INC (US) | 2023-05-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230286917-A1 | HISTONE DEMETHYLASE INHIBITORS | KDM1B, KDM5A, KDM1A | HRH3 309/4885RXRA 1998/4885RXRB 1590/4885 |
| US-11639333-B2 | Histone demethylase inhibitors | KDM1B, KDM5A, KDM1A | HRH3 309/4885RXRA 1998/4885RXRB 1590/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.