SCHEMBL30299207

SCHEMBL30299207

CC[C@H](C)[C@H](N)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)O

nearest known ligand 0.68

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
ERAP2 Q6P179 6/20 0.68
ECE1 P42892 6/20 0.66
EDNRA P25101 1/20 0.64
ACE P12821 2/20 0.62
IL1RN P18510 5/20 0.62
ERAP1 Q9NZ08 4/20 0.62
MMP2 P08253 2/20 0.57
MMP9 P14780 1/20 0.57
MMP8 P22894 1/20 0.57
MMP1 P03956 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29769026 0.99 ERAP2 (0.69) ERAP2ECE1EDNRAACEIL1RN
SCHEMBL30051527 0.97 ECE1 (0.64) ERAP2ECE1EDNRAACEIL1RN
SCHEMBL29379405 0.96 ERAP2 (0.64) ERAP2ECE1EDNRAACEIL1RN
SCHEMBL30051826 0.95 ACE (0.68) ERAP2ECE1ACE
SCHEMBL7397641 0.93 ACE (0.71) ECE1ACE
SCHEMBL5481232 0.93 ACE (0.71) ECE1ACE
SCHEMBL3512696 0.93 ACE (0.71) ECE1ACE
SCHEMBL8725890 0.93 ACE (0.71) ECE1ACE
SCHEMBL30052487 0.91 ACE (0.63) ERAP2ECE1ACE
SCHEMBL30053126 0.91 ACE (0.63) ERAP2ECE1ACE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4219805-B1 ANTIBODY LIBRARIES ADIMAB LLC (US) 2025-02-26 EP disclosed
US-20240352625-A1 LIBRARIES OF GENETIC PACKAGES COMPRISING NOVEL HC CDR3 DESIGNS TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2024-10-24 US disclosed
US-11926926-B2 Libraries of genetic packages comprising novel HC CDR3 designs TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2024-03-12 US disclosed
US-20230340697-A1 LIBRARIES OF GENETIC PACKAGES COMPRISING NOVEL HC CDR1, CDR2, AND CDR3 AND NOVEL LC CDR1, CDR2, AND CDR3 DESIGNS TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2023-10-26 US disclosed
EP-4219805-A1 ANTIBODY LIBRARIES Adimab, LLC (US) 2023-08-02 EP disclosed
US-11598024-B2 Libraries of genetic packages comprising novel HC CDR1, CDR2, and CDR3 and novel LC CDR1, CDR2, and CDR3 designs TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2023-03-07 US disclosed