Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.81 |
| ▸ | CA12 | O43570 | 2/20 | 0.61 |
| ▸ | CA2 | P00918 | 2/20 | 0.61 |
| ▸ | CA9 | Q16790 | 2/20 | 0.61 |
| ▸ | CA1 | P00915 | 1/20 | 0.61 |
| ▸ | MAOB | P27338 | 5/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | LMNA | P02545 | 3/20 | 0.54 |
| ▸ | MAPT | P10636 | 5/20 | 0.54 |
| ▸ | GAA | P10253 | 3/20 | 0.54 |
| ▸ | RAD52 | P43351 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2603636 | 1.00 | SIRT2 (0.81) | SIRT2CA12CA2CA9CA1 | |
| SCHEMBL3366755 | 1.00 | SIRT2 (0.81) | SIRT2CA12CA2CA9CA1 | |
| SCHEMBL2494083 | 0.90 | SIRT2 (1.00) | SIRT2CA12CA2CA9CA1 | |
| SCHEMBL2494084 | 0.90 | SIRT2 (1.00) | SIRT2CA12CA2CA9CA1 | |
| SCHEMBL10620538 | 0.85 | SIRT2 (0.88) | SIRT2CA12CA2CA9CA1 | |
| SCHEMBL30301787 | 0.85 | SIRT2 (0.88) | SIRT2CA12CA2CA9CA1 | |
| SCHEMBL10620536 | 0.85 | SIRT2 (0.88) | SIRT2CA12CA2CA9CA1 | |
| 2-((Phenylimino)Methyl)Phenol SCHEMBL347861 | 0.84 | SIRT2 (0.88) | SIRT2CA12CA2CA9CA1 | |
| 2-((Phenylimino)Methyl)Phenol SCHEMBL347862 | 0.84 | SIRT2 (0.88) | SIRT2CA12CA2CA9CA1 | |
| 2-((Phenylimino)Methyl)Phenol SCHEMBL29424118 | 0.84 | SIRT2 (0.88) | SIRT2CA12CA2CA9CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115745808-B | Method for preparing secondary amine compound by catalyzing reduction of imine compound | 延安大学 | 2024-04-30 | — | — | CN | disclosed |
| CN-115745808-A | Method for preparing secondary amine compound by catalyzing reduction of imine compound | 延安大学 | 2023-03-07 | — | — | CN | disclosed |