Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 1/20 | 0.64 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.64 |
| ▸ | DRD2 | P14416 | 5/20 | 0.54 |
| ▸ | DRD3 | P35462 | 5/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | CCKBR | P32239 | 1/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.51 |
| ▸ | HTR1D | P28221 | 2/20 | 0.51 |
| ▸ | HTR1B | P28222 | 2/20 | 0.51 |
| ▸ | HTR1A | P08908 | 1/20 | 0.51 |
| ▸ | HTR2A | P28223 | 1/20 | 0.51 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.50 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.50 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.50 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.50 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.50 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24076389 | 1.00 | SLC6A2 (0.64) | SLC6A2SLC6A4DRD2DRD3KDM4E | |
| SCHEMBL4018254 | 0.87 | KDM4E (0.62) | DRD2DRD3KDM4EALDH1A1GAA | |
| SCHEMBL24614077 | 0.84 | AKR1C3 (0.62) | DRD2DRD3KDM4EALDH1A1GAA | |
| SCHEMBL24614079 | 0.83 | DRD2 (0.54) | DRD2DRD3KDM4EALDH1A1GAA | |
| SCHEMBL76132 | 0.82 | MLLT1 (0.69) | KDM4EALDH1A1GAAMAPK1SMYD3 | |
| SCHEMBL75198 | 0.82 | MLLT1 (0.65) | DRD2DRD3KDM4EALDH1A1GAA | |
| SCHEMBL19837662 | 0.81 | NPC1 (0.56) | DRD2DRD3KDM4EALDH1A1GAA | |
| SCHEMBL21490113 | 0.81 | SMYD3 (0.71) | KDM4EALDH1A1GAAMAPK1SMYD3 | |
| SCHEMBL19710676 | 0.81 | SMYD3 (0.71) | KDM4EALDH1A1GAAMAPK1SMYD3 | |
| SCHEMBL19850663 | 0.81 | NPC1 (0.56) | DRD2DRD3KDM4EALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4159725-A1 | CARBOXAMIDE DERIVATIVE AND PHARMACEUTICAL COMPOSITION COMPRISING SAME AS ACTIVE INGREDIENT FOR PREVENTING OR TREATING MENTAL ILLNESS | Daegu-Gyeongbuk Medical Innovation Foundation (KR) | 2023-04-05 | — | — | EP | disclosed |