Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.65 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.64 |
| ▸ | DRD2 | P14416 | 1/20 | 0.64 |
| ▸ | DRD3 | P35462 | 1/20 | 0.64 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.62 |
| ▸ | HTR2C | P28335 | 1/20 | 0.62 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.61 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.61 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.61 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.61 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.61 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.61 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.61 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.61 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.61 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.61 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.61 |
| ▸ | GAA | P10253 | 1/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24076391 | 1.00 | KDM4E (0.65) | KDM4EALDH1A1HSD17B10DRD2DRD3 | |
| SCHEMBL28993896 | 0.84 | KDM4E (0.64) | KDM4EALDH1A1HSD17B10DRD2DRD3 | |
| SCHEMBL20267113 | 0.83 | KDM4E (0.72) | KDM4EALDH1A1HSD17B10DRD2DRD3 | |
| SCHEMBL27550290 | 0.83 | AKR1C3 (0.86) | KDM4EALDH1A1HSD17B10DRD2DRD3 | |
| SCHEMBL27015827 | 0.82 | KDM4E (0.60) | KDM4EALDH1A1HSD17B10DRD2DRD3 | |
| SCHEMBL30301414 | 0.82 | KDM4E (0.60) | KDM4EALDH1A1HSD17B10DRD2DRD3 | |
| SCHEMBL29904432 | 0.81 | KDM4E (0.83) | KDM4EALDH1A1HSD17B10DRD2DRD3 | |
| SCHEMBL14163702 | 0.81 | KDM4E (0.68) | KDM4EALDH1A1HSD17B10DRD2DRD3 | |
| SCHEMBL13753861 | 0.80 | DRD2 (0.84) | KDM4EALDH1A1HSD17B10DRD2DRD3 | |
| SCHEMBL27015810 | 0.80 | KDM4E (0.72) | KDM4EALDH1A1HSD17B10DRD2DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4159725-A1 | CARBOXAMIDE DERIVATIVE AND PHARMACEUTICAL COMPOSITION COMPRISING SAME AS ACTIVE INGREDIENT FOR PREVENTING OR TREATING MENTAL ILLNESS | Daegu-Gyeongbuk Medical Innovation Foundation (KR) | 2023-04-05 | — | — | EP | disclosed |