Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 19/20 | 0.79 |
| ▸ | LCK | P06239 | 4/20 | 0.79 |
| ▸ | LYN | P07948 | 2/20 | 0.79 |
| ▸ | NUDT14 | O95848 | 2/20 | 0.74 |
| ▸ | NUDT5 | Q9UKK9 | 2/20 | 0.74 |
| ▸ | SRC | P12931 | 2/20 | 0.69 |
| ▸ | KDR | P35968 | 1/20 | 0.69 |
| ▸ | TEK | Q02763 | 1/20 | 0.69 |
| ▸ | EGFR | P00533 | 3/20 | 0.65 |
| ▸ | ITK | Q08881 | 2/20 | 0.63 |
| ▸ | ABL1 | P00519 | 1/20 | 0.63 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.63 |
| ▸ | FYN | P06241 | 1/20 | 0.63 |
| ▸ | YES1 | P07947 | 1/20 | 0.63 |
| ▸ | HCK | P08631 | 1/20 | 0.63 |
| ▸ | FGR | P09769 | 1/20 | 0.63 |
| ▸ | FER | P16591 | 1/20 | 0.63 |
| ▸ | CSK | P41240 | 1/20 | 0.63 |
| ▸ | TEC | P42680 | 1/20 | 0.63 |
| ▸ | BLK | P51451 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5801169 | 0.92 | BTK (0.82) | BTKLCKLYNNUDT14NUDT5 | |
| SCHEMBL30301973 | 0.92 | BTK (0.77) | BTKLCKLYNNUDT14NUDT5 | |
| Hydrochloric Acid SCHEMBL21331506 | 0.91 | BTK (0.81) | BTKLCKLYNNUDT14NUDT5 | |
| SCHEMBL30586962 | 0.89 | BTK (1.00) | BTKLCKLYNNUDT14NUDT5 | |
| SCHEMBL6431516 | 0.89 | BTK (1.00) | BTKLCKLYNNUDT14NUDT5 | |
| SCHEMBL30225021 | 0.89 | BTK (0.77) | BTKLCKLYNNUDT14NUDT5 | |
| SCHEMBL30458561 | 0.89 | BTK (0.77) | BTKLCKLYNNUDT14NUDT5 | |
| SCHEMBL5803386 | 0.88 | BTK (0.76) | BTKLCKLYNNUDT14NUDT5 | |
| SCHEMBL14576054 | 0.88 | BTK (0.76) | BTKLCKLYNNUDT14NUDT5 | |
| SCHEMBL17713980 | 0.88 | BTK (0.98) | BTKLCKLYNNUDT14NUDT5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023104155-A1 | LIGAND COMPOUNDS FOR E3 UBIQUITIN LIGASE, PROTEIN DEGRADERS DEVELOPED ON BASIS OF LIGAND COMPOUNDS, AND USES THEREOF | 标新生物医药科技(上海)有限公司 | 2023-06-15 | — | — | WO | claimed |
| WO-2023072270-A1 | PROTAC COMPOUND, PHARMACEUTICAL COMPOSITION COMPRISING SAME, PREPARATION METHOD THEREFOR, AND USE THEREOF | 百极弘烨(南通)医药科技有限公司 | 2023-05-04 | — | — | WO | disclosed |