Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 20/20 | 0.77 |
| ▸ | LCK | P06239 | 3/20 | 0.77 |
| ▸ | LYN | P07948 | 3/20 | 0.77 |
| ▸ | NUDT14 | O95848 | 2/20 | 0.66 |
| ▸ | NUDT5 | Q9UKK9 | 2/20 | 0.66 |
| ▸ | SRC | P12931 | 2/20 | 0.62 |
| ▸ | KDR | P35968 | 2/20 | 0.62 |
| ▸ | TEK | Q02763 | 1/20 | 0.62 |
| ▸ | EGFR | P00533 | 4/20 | 0.60 |
| ▸ | TEC | P42680 | 3/20 | 0.60 |
| ▸ | BMX | P51813 | 3/20 | 0.60 |
| ▸ | TXK | P42681 | 2/20 | 0.60 |
| ▸ | FGFR2 | P21802 | 2/20 | 0.60 |
| ▸ | ITK | Q08881 | 2/20 | 0.60 |
| ▸ | BLK | P51451 | 2/20 | 0.60 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.60 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.60 |
| ▸ | SLC22A3 | O75751 | 1/20 | 0.60 |
| ▸ | LATS1 | O95835 | 1/20 | 0.60 |
| ▸ | ABL1 | P00519 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30225021 | 1.00 | BTK (0.77) | BTKLCKLYNNUDT14NUDT5 | |
| SCHEMBL29611773 | 0.91 | BTK (0.80) | BTKLCKLYNNUDT14NUDT5 | |
| SCHEMBL1614098 | 0.91 | BTK (0.80) | BTKLCKLYNNUDT14NUDT5 | |
| SCHEMBL17713765 | 0.91 | BTK (0.80) | BTKLCKLYNNUDT14NUDT5 | |
| SCHEMBL1614096 | 0.91 | BTK (0.80) | BTKLCKLYNNUDT14NUDT5 | |
| Hydrochloric Acid SCHEMBL17713741 | 0.90 | BTK (0.78) | BTKLCKLYNNUDT14NUDT5 | |
| Hydrochloric Acid SCHEMBL16931734 | 0.90 | BTK (0.78) | BTKLCKLYNNUDT14NUDT5 | |
| Hydrochloric Acid SCHEMBL17713743 | 0.90 | BTK (0.78) | BTKLCKLYNNUDT14NUDT5 | |
| Hydrochloric Acid SCHEMBL16931735 | 0.90 | BTK (0.78) | BTKLCKLYNNUDT14NUDT5 | |
| SCHEMBL30302001 | 0.89 | BTK (0.79) | BTKLCKLYNNUDT14NUDT5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023104155-A1 | LIGAND COMPOUNDS FOR E3 UBIQUITIN LIGASE, PROTEIN DEGRADERS DEVELOPED ON BASIS OF LIGAND COMPOUNDS, AND USES THEREOF | 标新生物医药科技(上海)有限公司 | 2023-06-15 | — | — | WO | claimed |