SCHEMBL30302156

SCHEMBL30302156

C[C@H](NC(=O)OCC1c2ccccc2-c2ccccc21)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(=O)NC(c1ccccc1)(c1ccccc1)c1ccccc1)C(=O)Nc1ccc(CO)cc1

nearest known ligand 0.45

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
▸ MDM4 O15151 1/20 0.39
▸ TP53 P04637 1/20 0.39
▸ PTPN1 P18031 5/20 0.39
▸ CASP3 P42574 4/20 0.39
▸ MDM2 Q00987 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22284883 0.93 MDM4 (0.42) MDM4TP53PTPN1CASP3MDM2
SCHEMBL17531773 0.93 MDM4 (0.42) MDM4TP53PTPN1CASP3MDM2
SCHEMBL31643427 0.89 MDM4 (0.48) MDM4TP53CASP3MDM2
SCHEMBL29528478 0.88 KMT2A (0.38) MDM4TP53PTPN1
SCHEMBL31720358 0.88 MDM4 (0.47) MDM4TP53PTPN1CASP3MDM2
SCHEMBL17531777 0.86 MEN1 (0.44) —
SCHEMBL30302162 0.86 PTPN1 (0.44) PTPN1CASP3
SCHEMBL19375786 0.85 MDM4 (0.43) MDM4TP53PTPN1CASP3MDM2
SCHEMBL30954823 0.85 EPHX2 (0.46) MDM4TP53PTPN1CASP3
SCHEMBL12683457 0.85 EPHX2 (0.46) MDM4TP53PTPN1CASP3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250367307-A1 PHARMACEUTICAL COMPOSITION FOR CANCER TREATMENT AND/OR PREVENTION TORAY INDUSTRIES, INC. (JP) 2025-12-04 — — US disclosed
US-20250281630-A1 PHARMACEUTICAL COMPOSITION FOR CANCER TREATMENT AND/OR PREVENTION TORAY INDUSTRIES, INC. (JP) 2025-09-11 — — US disclosed
US-20250249092-A1 CONJUGATE OF CAPRIN-1 ANTIBODY LINKED TO IMMUNE ACTIVATOR FOR CANCER TREATMENT TORAY INDUSTRIES, INC. (JP) 2025-08-07 — — US disclosed
EP-4548932-A1 PHARMACEUTICAL COMPOSITION FOR TREATING AND/OR PREVENTING CANCER Toray Industries, Inc. (JP) 2025-05-07 — — EP disclosed
US-12274745-B2 Conjugate of CAPRIN-1 antibody linked to immune activator for cancer treatment TORAY INDUSTRIES, INC. (JP) 2025-04-15 — — US disclosed
WO-2025058000-A1 PHARMACEUTICAL COMPOSITION FOR TREATING, PREVENTING AND/OR DIAGNOSING CANCER 東レ株式会社 2025-03-20 — — WO disclosed
EP-4400121-A1 PHARMACEUTICAL COMPOSITION FOR TREATING AND/OR PREVENTING CANCER Toray Industries, Inc. (JP) 2024-07-17 — — EP disclosed
WO-2023033129-A1 PHARMACEUTICAL COMPOSITION FOR TREATING AND/OR PREVENTING CANCER 東レ株式会社 2023-03-09 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250367307-A1 PHARMACEUTICAL COMPOSITION FOR CANCER TREATMENT AND/OR PREVENTION CAPRIN1, NOS1, NCBP1 MDM4 2219/4885TP53 116/4885PTPN1 2463/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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