⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1162 | 0.97 | — | — | |
| SCHEMBL27677215 | 0.97 | MGAM (1.00) | — | |
| SCHEMBL11019941 | 0.94 | — | — | |
| SCHEMBL9248466 | 0.94 | MGAM (0.94) | — | |
| SCHEMBL7727653 | 0.94 | MGAM (0.94) | — | |
| SCHEMBL303752 | 0.94 | — | — | |
| SCHEMBL17433643 | 0.94 | MGAM (0.94) | — | |
| SCHEMBL303851 | 0.94 | — | — | |
| SCHEMBL20942931 | 0.94 | — | — | |
| SCHEMBL8200369 | 0.94 | MGAM (0.94) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2012500848-A | — | — | 2012-01-12 | — | — | JP | claimed |
| US-8044214-B2 | Process for preparing isoxazole compounds | ANGUS CHEMICAL COMPANY (US) | 2011-10-25 | — | — | US | claimed |
| EP-2318381-A1 | PROCESS FOR PREPARING ISOXAZOLE COMPOUNDS | Dow Global Technologies LLC (US) | 2011-05-11 | — | — | EP | claimed |
| WO-2010025035-A1 | PROCESS FOR PREPARING ISOXAZOLE COMPOUNDS | DOW GLOBAL TECHNOLOGIES INC. (US) | 2010-03-04 | — | — | WO | claimed |
| US-20100048910-A1 | PROCESS FOR PREPARING ISOXAZOLE COMPOUNDS | ANGUS CHEMICAL COMPANY | 2010-02-25 | — | — | US | claimed |
| US-8044214-B2 | Process for preparing isoxazole compounds | ANGUS CHEMICAL COMPANY (US) | 2011-10-25 | — | — | US | disclosed |
| EP-2318381-A1 | PROCESS FOR PREPARING ISOXAZOLE COMPOUNDS | Dow Global Technologies LLC (US) | 2011-05-11 | — | — | EP | disclosed |
| WO-2010025035-A1 | PROCESS FOR PREPARING ISOXAZOLE COMPOUNDS | DOW GLOBAL TECHNOLOGIES INC. (US) | 2010-03-04 | — | — | WO | disclosed |
| US-20100048910-A1 | PROCESS FOR PREPARING ISOXAZOLE COMPOUNDS | ANGUS CHEMICAL COMPANY | 2010-02-25 | — | — | US | disclosed |