Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | PKM | P14618 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | HTR2C | P28335 | 2/20 | 0.46 |
| ▸ | HTR2B | P41595 | 2/20 | 0.46 |
| ▸ | ERN1 | O75460 | 1/20 | 0.46 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.46 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.44 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14785176 | 1.00 | KMT2A (0.56) | KMT2AALDH1A1PKMKDM4EHPGD | |
| SCHEMBL28953715 | 0.89 | ALDH1A1 (0.55) | KMT2AALDH1A1PKMKDM4EHPGD | |
| SCHEMBL30902394 | 0.88 | HPGD (0.64) | KMT2AALDH1A1PKMKDM4EHPGD | |
| SCHEMBL1185190 | 0.88 | HPGD (0.64) | KMT2AALDH1A1PKMKDM4EHPGD | |
| SCHEMBL6097520 | 0.87 | ERN1 (0.50) | KMT2AALDH1A1PKMKDM4EHPGD | |
| SCHEMBL29189167 | 0.85 | ALDH1A1 (0.54) | ALDH1A1PKMKDM4EHPGDTSHR | |
| SCHEMBL30304244 | 0.85 | ALDH1A1 (0.54) | ALDH1A1PKMKDM4EHPGDTSHR | |
| SCHEMBL30902395 | 0.83 | ERN1 (0.50) | KMT2AALDH1A1PKMKDM4EHPGD | |
| SCHEMBL5882305 | 0.83 | ERN1 (0.50) | KMT2AALDH1A1PKMKDM4EHPGD | |
| SCHEMBL1186559 | 0.82 | HPGD (0.50) | KMT2AALDH1A1PKMKDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4619097-A1 | AUTOPHAGY INDUCING COMPOUNDS AND USES THEREOF | Samsara Therapeutics Inc. (US) | 2025-09-24 | — | — | EP | disclosed |
| WO-2025106477-A1 | NOVEL AUTOPHAGY INDUCING COMPOUNDS AND USES THEREOF | Samsara Therapeutics Inc. (US) | 2025-05-22 | — | — | WO | disclosed |
| WO-2024107434-A1 | AUTOPHAGY INDUCING COMPOUNDS AND USES THEREOF | Samsara Therapeutics Inc. (US) | 2024-05-23 | — | — | WO | disclosed |
| WO-2024105007-A1 | AUTOPHAGY INDUCING COMPOUNDS AND USES THEREOF | Samsara Therapeutics Inc. (US) | 2024-05-23 | — | — | WO | disclosed |
| CN-116041230-B | NLRP3 inflammation small inhibitor and preparation method and application thereof | 中国海洋大学 | 2024-03-19 | — | — | CN | disclosed |
| CN-116041230-A | NLRP3 inflammation small inhibitor and preparation method and application thereof | 中国海洋大学 | 2023-05-02 | — | — | CN | disclosed |