Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC25B | P30305 | 5/20 | 0.64 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.55 |
| ▸ | CDC25A | P30304 | 1/20 | 0.54 |
| ▸ | CDC25C | P30307 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.52 |
| ▸ | MEN1 | O00255 | 4/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.50 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.50 |
| ▸ | IGF1R | P08069 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12809946 | 0.82 | CDC25B (0.59) | CDC25BMAPK14CDC25ACDC25CKMT2A | |
| SCHEMBL22757436 | 0.81 | CDC25B (0.54) | CDC25BMAPK14CDC25ACDC25CKMT2A | |
| SCHEMBL18257226 | 0.80 | KMT2A (0.56) | CDC25BMAPK14CDC25ACDC25CKMT2A | |
| SCHEMBL13352354 | 0.78 | CDC25B (0.56) | CDC25BCDC25ACDC25CKMT2AMEN1 | |
| SCHEMBL1408380 | 0.78 | CDC25B (0.71) | CDC25BCDC25ACDC25CALDH1A1HPGD | |
| SCHEMBL6536796 | 0.77 | CDC25B (0.55) | CDC25BMAPK14CDC25ACDC25CKMT2A | |
| SCHEMBL27635348 | 0.77 | MEN1 (0.46) | CDC25BKMT2AMEN1KDM4EALDH1A1 | |
| SCHEMBL22556212 | 0.77 | KMT2A (0.73) | KMT2AMEN1KDM4EALDH1A1HPGD | |
| SCHEMBL1162404 | 0.76 | CDC25B (0.80) | CDC25BKMT2AMEN1KDM4EALDH1A1 | |
| SCHEMBL18257190 | 0.76 | SMN1; SMN2 (0.66) | KMT2AMEN1ALDH1A1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115836072-A | Inhibitors of KRAS G12C protein and uses thereof | 上海德琪医药科技有限公司 | 2023-03-21 | — | — | CN | disclosed |