Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC25B | P30305 | 6/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | CDC25A | P30304 | 1/20 | 0.47 |
| ▸ | CDC25C | P30307 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.44 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | CASP3 | P42574 | 2/20 | 0.43 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.43 |
| ▸ | APAF1 | O14727 | 1/20 | 0.43 |
| ▸ | TDP2 | O95551 | 1/20 | 0.43 |
| ▸ | CASP7 | P55210 | 1/20 | 0.43 |
| ▸ | CASP9 | P55211 | 1/20 | 0.43 |
| ▸ | CASP6 | P55212 | 1/20 | 0.43 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.43 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6536796 | 0.84 | CDC25B (0.55) | CDC25BCYP1A2CYP2A6RAB9ACDC25A | |
| SCHEMBL1408380 | 0.81 | CDC25B (0.71) | CDC25BRAB9ACDC25ACDC25CALDH1A1 | |
| SCHEMBL27937841 | 0.80 | CDC25B (0.40) | CDC25BCYP1A2CDC25ACDC25CKMT2A | |
| SCHEMBL30305264 | 0.78 | CDC25B (0.64) | CDC25BRAB9ACDC25ACDC25CKMT2A | |
| SCHEMBL29370537 | 0.75 | NQO1 (0.57) | CDC25BCYP1A2CYP2A6KMT2AMEN1 | |
| SCHEMBL4433796 | 0.75 | CYP2A6 (0.57) | CYP1A2CYP2A6RAB9AKMT2AMEN1 | |
| SCHEMBL30011882 | 0.75 | CYP1A2 (0.54) | CDC25BCYP1A2CYP2A6KMT2AMEN1 | |
| SCHEMBL443362 | 0.75 | NQO1 (0.57) | CDC25BCYP1A2CYP2A6KMT2AMEN1 | |
| SCHEMBL5782272 | 0.75 | CYP1A2 (0.54) | CDC25BCYP1A2CYP2A6KMT2AMEN1 | |
| SCHEMBL1161428 | 0.75 | CYP2A6 (0.57) | CDC25BCYP1A2CYP2A6RAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2186801-A2 | Intermediates for synthesizing dibenzorhodamine dyes | Applera Corporation (US) | 2010-05-19 | — | — | EP | disclosed |