Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B2 | P19099 | 1/20 | 0.61 |
| ▸ | GRM1 | Q13255 | 9/20 | 0.49 |
| ▸ | NAMPT | P43490 | 1/20 | 0.49 |
| ▸ | GRM5 | P41594 | 9/20 | 0.48 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.47 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.46 |
| ▸ | BTK | Q06187 | 1/20 | 0.45 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.45 |
| ▸ | TNK2 | Q07912 | 2/20 | 0.45 |
| ▸ | CDK7 | P50613 | 1/20 | 0.44 |
| ▸ | CDK13 | Q14004 | 1/20 | 0.44 |
| ▸ | CDK12 | Q9NYV4 | 1/20 | 0.44 |
| ▸ | JAK1 | P23458 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16271570 | 1.00 | CYP11B2 (0.61) | CYP11B2GRM1NAMPTGRM5PDK4 | |
| SCHEMBL13473291 | 0.88 | CYP11B2 (0.61) | CYP11B2GRM1NAMPTGRM5PDK4 | |
| SCHEMBL29760157 | 0.88 | CYP11B2 (0.48) | CYP11B2GRM1NAMPTGRM5PDK4 | |
| SCHEMBL16271602 | 0.88 | CYP11B2 (0.48) | CYP11B2GRM1NAMPTGRM5PDK4 | |
| SCHEMBL30032127 | 0.86 | CYP11B2 (0.59) | CYP11B2GRM1NAMPTGRM5PDK4 | |
| SCHEMBL4163933 | 0.86 | CYP11B2 (0.59) | CYP11B2GRM1NAMPTGRM5PDK4 | |
| SCHEMBL30191814 | 0.86 | CYP11B2 (0.59) | CYP11B2GRM1NAMPTGRM5PDK4 | |
| SCHEMBL2883881 | 0.86 | CYP11B2 (0.59) | CYP11B2GRM1NAMPTGRM5PDK4 | |
| SCHEMBL20753874 | 0.85 | CYP11B2 (0.58) | CYP11B2GRM1NAMPTGRM5PDK4 | |
| SCHEMBL29580862 | 0.85 | CYP11B2 (0.58) | CYP11B2GRM1NAMPTGRM5PDK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111225910-B | Novel compounds | 葛兰素史密斯克莱知识产权发展有限公司 | 2023-03-24 | — | — | CN | disclosed |