Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | DPP4 | P27487 | 6/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.38 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.38 |
| ▸ | ACE | P12821 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8591233 | 1.00 | HTT (0.45) | HTTDPP4CA12CA1CA2 | |
| SCHEMBL3817074 | 1.00 | HTT (0.45) | HTTDPP4CA12CA1CA2 | |
| SCHEMBL6447711 | 0.93 | CA12 (0.42) | HTTDPP4CA12CA1CA2 | |
| SCHEMBL6447709 | 0.93 | CA12 (0.42) | HTTDPP4CA12CA1CA2 | |
| SCHEMBL29098712 | 0.86 | SMN1; SMN2 (0.34) | HTTDPP4 | |
| SCHEMBL4492387 | 0.84 | DPP4 (0.43) | DPP4CA12CA1CA2CA9 | |
| SCHEMBL3840600 | 0.84 | DPP4 (0.43) | DPP4CA12CA1CA2CA9 | |
| SCHEMBL475439 | 0.84 | DPP4 (0.43) | DPP4CA12CA1CA2CA9 | |
| SCHEMBL1442233 | 0.84 | LMNA (0.54) | LMNACYP2C19HSD17B10ACE | |
| SCHEMBL30305374 | 0.84 | LMNA (0.54) | LMNACYP2C19HSD17B10ACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111995541-B | Compounds containing amide functionality of stable heavy isotopes and uses thereof | 君实润佳(上海)医药科技有限公司 | 2025-05-06 | — | — | CN | disclosed |
| CN-117942338-A | Pharmaceutical use of isotopically enriched compounds in PROS | 君实润佳(上海)医药科技有限公司 | 2024-04-30 | — | — | CN | disclosed |
| CN-115835888-A | Stable heavy isotopes in amide functions and uses thereof | 润佳（苏州）医药科技有限公司 | 2023-03-21 | — | — | CN | disclosed |