Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD9 | Q9H8M2 | 8/20 | 0.74 |
| ▸ | BRD4 | O60885 | 9/20 | 0.66 |
| ▸ | TAF1 | P21675 | 5/20 | 0.64 |
| ▸ | CECR2 | Q9BXF3 | 4/20 | 0.64 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.64 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.64 |
| ▸ | SMARCA4 | P51532 | 1/20 | 0.64 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.64 |
| ▸ | EP300 | Q09472 | 1/20 | 0.64 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.64 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.64 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.64 |
| ▸ | BAZ2A | Q9UIF9 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31590453 | 0.87 | BRD4 (0.66) | BRD9BRD4TAF1CECR2TRIM24 | |
| SCHEMBL17756347 | 0.85 | BRD9 (1.00) | BRD9BRD4TAF1CECR2 | |
| SCHEMBL22827390 | 0.80 | BRD4 (0.57) | BRD9BRD4CECR2 | |
| SCHEMBL17748871 | 0.80 | BRD4 (1.00) | BRD9BRD4TAF1CECR2TRIM24 | |
| SCHEMBL17748894 | 0.79 | BRD4 (1.00) | BRD9BRD4TAF1CECR2TRIM24 | |
| SCHEMBL17748926 | 0.78 | BRD4 (1.00) | BRD9BRD4TAF1CECR2TRIM24 | |
| SCHEMBL17748918 | 0.78 | TAF1 (1.00) | BRD9BRD4TAF1CECR2TRIM24 | |
| SCHEMBL17748947 | 0.78 | CECR2 (1.00) | BRD9BRD4TAF1CECR2TRIM24 | |
| SCHEMBL27363388 | 0.76 | BRD4 (0.72) | BRD4 | |
| SCHEMBL27362199 | 0.76 | BRD4 (0.59) | BRD9BRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112094266-B | Pyrrolopyridinone compound, preparation method, composition and application thereof | 中国科学院上海药物研究所 | 2023-03-21 | — | — | CN | disclosed |