Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 17/20 | 0.77 |
| ▸ | ALDH1A1 | P00352 | 15/20 | 0.73 |
| ▸ | HSD17B10 | Q99714 | 11/20 | 0.73 |
| ▸ | PKM | P14618 | 4/20 | 0.73 |
| ▸ | RECQL | P46063 | 1/20 | 0.73 |
| ▸ | TSHR | P16473 | 4/20 | 0.72 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.72 |
| ▸ | MAPT | P10636 | 3/20 | 0.72 |
| ▸ | HPGD | P15428 | 7/20 | 0.70 |
| ▸ | HTT | P42858 | 4/20 | 0.70 |
| ▸ | LMNA | P02545 | 3/20 | 0.70 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.70 |
| ▸ | ALOX15 | P16050 | 5/20 | 0.69 |
| ▸ | NPC1 | O15118 | 1/20 | 0.69 |
| ▸ | USP2 | O75604 | 1/20 | 0.69 |
| ▸ | GAA | P10253 | 1/20 | 0.68 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.64 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.63 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12595343 | 0.87 | KDM4E (0.79) | KDM4EALDH1A1HSD17B10TSHRNPSR1 | |
| SCHEMBL13496428 | 0.87 | KDM4E (1.00) | KDM4EALDH1A1HSD17B10PKMRECQL | |
| SCHEMBL12595339 | 0.84 | KDM4E (0.73) | KDM4EALDH1A1HSD17B10TSHRNPSR1 | |
| SCHEMBL13496443 | 0.84 | KDM4E (1.00) | KDM4EALDH1A1HSD17B10TSHRNPSR1 | |
| SCHEMBL12594151 | 0.83 | ALDH1A1 (0.77) | KDM4EALDH1A1HSD17B10TSHRNPSR1 | |
| SCHEMBL12594568 | 0.83 | KDM4E (0.82) | KDM4EALDH1A1HSD17B10TSHRNPSR1 | |
| SCHEMBL12594558 | 0.83 | ALDH1A1 (1.00) | KDM4EALDH1A1HSD17B10TSHRNPSR1 | |
| SCHEMBL30307323 | 0.79 | ALDH1A1 (0.70) | KDM4EALDH1A1HSD17B10PKMTSHR | |
| SCHEMBL13496405 | 0.78 | ALDH1A1 (1.00) | KDM4EALDH1A1HSD17B10PKMRECQL | |
| SCHEMBL12594152 | 0.77 | ALDH1A1 (0.73) | KDM4EALDH1A1HSD17B10TSHRNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240366586-A1 | METHODS AND AGENTS FOR MODULATING THE IMMUNE RESPONSE | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2024-11-07 | — | — | US | claimed |
| WO-2023034413-A2 | METHODS AND AGENTS FOR MODULATING THE IMMUNE RESPONSE | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2023-03-09 | — | — | WO | claimed |
| US-20240366586-A1 | METHODS AND AGENTS FOR MODULATING THE IMMUNE RESPONSE | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2024-11-07 | — | — | US | disclosed |
| WO-2023034413-A2 | METHODS AND AGENTS FOR MODULATING THE IMMUNE RESPONSE | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2023-03-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240366586-A1 | METHODS AND AGENTS FOR MODULATING THE IMMUNE RESPONSE | IL15, IL2, IL17A | KDM4E 1626/4885ALDH1A1 3528/4885HSD17B10 1346/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.