Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | APEX1 | P27695 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.30 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.30 |
| ▸ | HPGDS | O60760 | 1/20 | 0.30 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12231778 | 1.00 | TNKS2 (0.34) | TNKS2POLBAPEX1HTTTDP1 | |
| SCHEMBL8620062 | 0.95 | NPC1 (0.34) | POLBAPEX1HTTTDP1NPC1 | |
| SCHEMBL25282759 | 0.91 | POLB (0.32) | POLBAPEX1HTTTDP1MAPT | |
| SCHEMBL14213069 | 0.89 | NPC1 (0.34) | TNKS2POLBAPEX1HTTTDP1 | |
| SCHEMBL3880166 | 0.89 | GAA (0.36) | TNKS2POLBAPEX1HTTTDP1 | |
| SCHEMBL29716387 | 0.89 | GAA (0.36) | TNKS2POLBAPEX1HTTTDP1 | |
| SCHEMBL12128112 | 0.89 | GAA (0.33) | TNKS2POLBAPEX1HTTTDP1 | |
| SCHEMBL292630 | 0.89 | POLB (0.39) | POLBAPEX1HTTTDP1NPC1 | |
| SCHEMBL29399137 | 0.89 | POLB (0.39) | POLBAPEX1HTTTDP1NPC1 | |
| SCHEMBL29370220 | 0.89 | GAA (0.33) | TNKS2POLBAPEX1HTTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3805290-B1 | POLYMER MATERIAL AND INTRAOCULAR LENS | SHANGHAI FULO MEDICAL INSTR CO LTD (CN) | 2024-09-11 | — | — | EP | claimed |
| EP-3805290-B1 | POLYMER MATERIAL AND INTRAOCULAR LENS | SHANGHAI FULO MEDICAL INSTR CO LTD (CN) | 2024-09-11 | — | — | EP | disclosed |
| CN-112204073-B | Polymeric material and intraocular lens | 上海富吉医疗器械有限公司 | 2023-05-09 | — | — | CN | disclosed |