SCHEMBL29370220

SCHEMBL29370220

C=C(C)C(=O)OCCCc1cc(-n2nc3ccc(Cl)cc3n2)c(O)c(C(C)(C)C)c1

nearest known ligand 0.36

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
GAA P10253 2/20 0.33
TLR8 Q9NR97 1/20 0.32
TNKS2 Q9H2K2 1/20 0.30
POLB P06746 1/20 0.30
APEX1 P27695 1/20 0.30
HTT P42858 1/20 0.30
TDP1 Q9NUW8 1/20 0.30
KDM4E B2RXH2 1/20 0.30
ALDH1A1 P00352 1/20 0.30
LMNA P02545 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30
MAOA P21397 1/20 0.30
MAOB P27338 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL227535 1.00 GAA (0.33) GAATLR8TNKS2POLBAPEX1
SCHEMBL29384523 0.95 GAA (0.31) GAAHTTMAOAMAOB
SCHEMBL93350 0.95 GAA (0.31) GAAHTTMAOAMAOB
SCHEMBL14213069 0.90 NPC1 (0.34) GAATNKS2POLBAPEX1HTT
SCHEMBL25282759 0.90 POLB (0.32) POLBAPEX1HTTTDP1
SCHEMBL3880166 0.90 GAA (0.36) GAATNKS2POLBAPEX1HTT
SCHEMBL29716387 0.90 GAA (0.36) GAATNKS2POLBAPEX1HTT
SCHEMBL12128112 0.89 GAA (0.33) GAATNKS2POLBAPEX1HTT
SCHEMBL1973788 0.89 RXFP1 (0.33) GAAHTTKDM4EALDH1A1
SCHEMBL12231778 0.89 TNKS2 (0.34) GAATNKS2POLBAPEX1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 147 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4519721-B1 RADIATION BLOCKERS FOR CONTACT LENSES COOPERVISION INT LTD (GB) 2025-10-01 EP claimed
EP-4529621-A1 UV/HEVL-FILTERING CONTACT LENSES Alcon Inc. (CH) 2025-04-02 EP claimed
CN-119137510-A UV/HEVL filtering contact lenses 爱尔康公司 2024-12-13 CN claimed
WO-2023228055-A1 UV/HEVL-FILTERING CONTACT LENSES ALCON INC. (CH) 2023-11-30 WO claimed
EP-4720728-A1 COATED SILICONE HYDROGEL CONTACT LENSES AND METHOD FOR MAKING THE SAME Alcon Inc. (CH) 2026-04-08 EP disclosed
EP-4719751-A1 METHOD FOR MAKING EMBEDDED HYDROGEL CONTACT LENSES Alcon Inc. (CH) 2026-04-08 EP disclosed
EP-4719753-A1 METHOD FOR MAKING EMBEDDED HYDROGEL CONTACT LENSES Alcon Inc. (CH) 2026-04-08 EP disclosed
EP-4719750-A1 EMBEDDED HYDROGEL CONTACT LENSES Alcon Inc. (CH) 2026-04-08 EP disclosed
US-20260042268-A1 SILICONE HYDROGEL LENSES WITH WATER-RICH SURFACES ALCON INC (CH) 2026-02-12 US disclosed
EP-4688952-A1 POLYMER COMPOSITION WITH FLAME AND ELECTRICAL TRACKING RESISTANCE Celanese International Corporation (US) 2026-02-11 EP disclosed
EP-4657144-A2 SILICONE HYDROGEL LENSES WITH WATER-RICH SURFACES Alcon Inc. (CH) 2025-12-03 EP disclosed
EP-4657145-A2 SILICONE HYDROGEL LENSES WITH WATER-RICH SURFACES Alcon Inc. (CH) 2025-12-03 EP disclosed
WO-2022097048-A1 METHOD FOR MAKING PHOTOCHROMIC CONTACT LENSES ALCON INC. (CH) 2022-05-12 WO disclosed
WO-2022097049-A1 METHOD FOR MAKING PHOTOCHROMIC CONTACT LENSES ALCON INC. (CH) 2022-05-12 WO disclosed
WO-2022090967-A1 METHOD FOR MAKING PHOTOCHROMIC CONTACT LENSES ALCON INC. (CH) 2022-05-05 WO disclosed
EP-3990549-A1 FLAME RESISTANT POLYMER COMPOSITION AND ARTICLES MADE THEREFROM Celanese International Corporation (US) 2022-05-04 EP disclosed
CN-114341269-A Flame retardant polymer compositions and articles made therefrom 国际人造丝公司 2022-04-12 CN disclosed
CN-111032829-B Composition and flame-retardant resin composition 株式会社艾迪科 2022-03-22 CN disclosed
CN-111065674-B Composition, thermoplastic resin composition using the same, and molded article thereof 株式会社ADEKA 2022-02-22 CN disclosed
CN-111051412-B Composition, thermoplastic resin composition using the same, and molded article thereof 株式会社ADEKA 2022-02-08 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260042268-A1 SILICONE HYDROGEL LENSES WITH WATER-RICH SURFACES STRA6, CRYZ, SMCHD1 GAA 3183/4885TLR8 1208/4885TNKS2 4803/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.