Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 1/20 | 0.46 |
| ▸ | ALPG | P10696 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 9/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.43 |
| ▸ | TP53 | P04637 | 4/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.42 |
| ▸ | NQO1 | P15559 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | HPGD | P15428 | 4/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 5/20 | 0.41 |
| ▸ | RAB9A | P51151 | 5/20 | 0.41 |
| ▸ | CSNK2A2 | P19784 | 4/20 | 0.41 |
| ▸ | CSNK2B | P67870 | 4/20 | 0.41 |
| ▸ | CSNK2A1 | P68400 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3456496 | 0.83 | MAOA (0.50) | ELANEMAPTKDM4ETP53ALDH1A1 | |
| SCHEMBL25218390 | 0.81 | ELANE (0.40) | ELANEALPGMAPTKDM4ETP53 | |
| SCHEMBL31217594 | 0.76 | ALPG (0.48) | ALPGMAPTKDM4ETP53RXFP1 | |
| SCHEMBL1611070 | 0.74 | ALPG (0.59) | ALPGMAPTKDM4ETP53NQO1 | |
| SCHEMBL29171533 | 0.74 | MAPT (0.52) | ELANEMAPTKDM4ETP53ALDH1A1 | |
| SCHEMBL23886990 | 0.74 | ESR1 (0.36) | ELANECSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL6471093 | 0.72 | ALPG (0.67) | ALPGMAPTKDM4ETP53NQO1 | |
| SCHEMBL30889653 | 0.72 | ELANE (0.48) | ELANEMAPTNPC1RAB9A | |
| SCHEMBL29003812 | 0.71 | ELANE (0.34) | ELANE | |
| SCHEMBL31035264 | 0.71 | ALPG (0.49) | ALPGMAPTKDM4ETP53RXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115956075-A | Allosteric enone inhibitors of phosphoinositide 3-kinases (PI 3 ks) for the treatment of diseases associated with PI3K modulation | 佩特拉制药公司 | 2023-04-11 | — | — | CN | disclosed |