SCHEMBL30307616

CC[C@H](C)[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CC(=O)O)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CO)NC(=O)[C@H](CC(=O)O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](CC(=O)O)NC(=O)[C@H](CC(N)=O)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H](NC(=O)CNC(=O)[C@H](CCC(N)=O)NC(=O)[C@@H](CO)NC(=O)[C@@H](N)Cc1c[nH]cn1)[C@@H](C)O)[C@@H](C)O)C(C)C)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)NCC(=O)N1CCC[C@H]1C(=O)N[C@@H](CO)C(=O)N[C@@H](CO)C(=O)NCC(=O)N[C@@H](C)C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)N[C@@H](CO)C(=O)O

nearest known ligand 0.80

Predicted protein targets (top 8)

	gene	UniProt	supporting neighbours	confidence
▸	GLP1R	P43220	18/20	0.80

▸	GCGR	P47871	9/20	0.80

▸	GIPR	P48546	9/20	0.75

▸	CCKBR	P32239	2/20	0.73

▸	NPY1R	P25929	1/20	0.72

▸	NPY2R	P49146	1/20	0.72

▸	NPY4R	P50391	1/20	0.72

▸	NPY5R	Q15761	1/20	0.72

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL30307619	1.00	GLP1R (0.80)	GLP1RGCGRGIPRCCKBRNPY1R
SCHEMBL29367539	0.99	GLP1R (0.80)	GLP1RGCGRGIPRCCKBRNPY1R
SCHEMBL29367233	0.99	GLP1R (0.80)	GLP1RGCGRGIPRCCKBRNPY1R
SCHEMBL29364819	0.96	GLP1R (0.81)	GLP1RGCGRGIPRCCKBR
SCHEMBL30645490	0.95	GLP1R (0.80)	GLP1RGCGRGIPRCCKBR
SCHEMBL29576071	0.95	GLP1R (0.80)	GLP1RGCGRGIPRCCKBR
SCHEMBL30460356	0.95	GLP1R (0.80)	GLP1RGCGRGIPRCCKBR
SCHEMBL30473764	0.95	GLP1R (0.80)	GLP1RGCGRGIPRCCKBR
SCHEMBL30473786	0.95	GLP1R (0.79)	GLP1RGCGRGIPRCCKBRNPY1R
SCHEMBL30473790	0.95	GLP1R (0.79)	GLP1RGCGRGIPRCCKBRNPY1R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
CN-115819551-A	GLP-1/glucagon/gastrin receptor triple agonist with site-specific modification and application thereof	南京赛诺生物制药有限公司	2023-03-21	—	—	CN	claimed