SCHEMBL30307751

SCHEMBL30307751

Brc1c2cc(-c3ccccc3)ccc2c(-c2ccccc2)c2cc(-c3ccccc3)ccc12

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.41
MAPK1 P28482 2/20 0.41
GRIN2D O15399 1/20 0.41
GRIN2A Q12879 1/20 0.41
GRIN2B Q13224 1/20 0.41
GRIN2C Q14957 1/20 0.41
ESR1 P03372 2/20 0.40
ESR2 Q92731 2/20 0.40
KDM4E B2RXH2 2/20 0.37
MAPT P10636 2/20 0.37
TDP1 Q9NUW8 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
ALOX5 P09917 1/20 0.36
JAK2 O60674 2/20 0.36
HSD17B1 P14061 2/20 0.36
HSD17B2 P37059 2/20 0.36
CYP1A2 P05177 1/20 0.36
CYP3A4 P08684 1/20 0.36
CYP2D6 P10635 1/20 0.36
CYP2C9 P11712 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26086587 1.00 ALDH1A1 (0.41) ALDH1A1MAPK1GRIN2DGRIN2AGRIN2B
SCHEMBL19283273 0.96 ALDH1A1 (0.41) ALDH1A1MAPK1GRIN2DGRIN2AGRIN2B
SCHEMBL21517233 0.96 ALDH1A1 (0.41) ALDH1A1MAPK1GRIN2DGRIN2AGRIN2B
SCHEMBL17125452 0.96 ALDH1A1 (0.41) ALDH1A1MAPK1GRIN2DGRIN2AGRIN2B
SCHEMBL276393 0.96 ALDH1A1 (0.41) ALDH1A1MAPK1GRIN2DGRIN2AGRIN2B
SCHEMBL25625159 0.96 ALDH1A1 (0.41) ALDH1A1MAPK1GRIN2DGRIN2AGRIN2B
SCHEMBL26384351 0.94 ALDH1A1 (0.43) ALDH1A1MAPK1GRIN2DGRIN2AGRIN2B
SCHEMBL17366608 0.92 ALDH1A1 (0.41) ALDH1A1MAPK1GRIN2DGRIN2AGRIN2B
SCHEMBL29396610 0.90 ALDH1A1 (0.50) ALDH1A1MAPK1GRIN2DGRIN2AGRIN2B
SCHEMBL9971879 0.90 ALDH1A1 (0.50) ALDH1A1MAPK1GRIN2DGRIN2AGRIN2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115819324-A Organic compounds 株式会社半导体能源研究所 2023-03-21 CN disclosed