SCHEMBL30308732

SCHEMBL30308732

CC[C@H](C)[C@H](NC(=O)[C@H](C)NC(=O)[C@@H](N)CO)C(=O)N[C@@H](CCCNC(=N)N)C(=O)NCC(=O)N[C@@H](C)C(=O)O

nearest known ligand 0.41

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
▸ RXFP1 Q9HBX9 2/20 0.41
▸ OPRL1 P41146 3/20 0.39
▸ TFPI P10646 1/20 0.37
▸ NPY5R Q15761 3/20 0.37
▸ NPY1R P25929 2/20 0.37
▸ NPY4R P50391 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30774306 0.85 OPRL1 (0.43) OPRL1
SCHEMBL29822483 0.85 CCNA2 (0.40) OPRL1
SCHEMBL30819872 0.85 RXFP1 (0.49) RXFP1TFPI
SCHEMBL31757515 0.84 RXFP1 (0.50) RXFP1OPRL1TFPI
SCHEMBL30121216 0.84 NPY4R (0.48) RXFP1NPY5RNPY1RNPY4R
SCHEMBL27766446 0.84 ENPEP (0.46) —
SCHEMBL30611007 0.83 NPY4R (0.44) NPY5RNPY1RNPY4R
SCHEMBL4082293 0.83 NPY4R (0.41) NPY5RNPY1RNPY4R
SCHEMBL4082284 0.83 NPY4R (0.41) NPY5RNPY1RNPY4R
SCHEMBL29678410 0.83 NPY4R (0.47) RXFP1NPY5RNPY1RNPY4R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11542508-B2 Isolated polynucleotides and polypeptides and methods of using same for expressing an expression product of interest YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) 2023-01-03 — — US disclosed
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