Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPHK2 | Q9NRA0 | 6/20 | 0.38 |
| ▸ | SPHK1 | Q9NYA1 | 6/20 | 0.38 |
| ▸ | MEN1 | O00255 | 5/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | CETP | P11597 | 4/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.38 |
| ▸ | THRB | P10828 | 3/20 | 0.38 |
| ▸ | GMNN | O75496 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | GLA | P06280 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | CXCR5 | P32302 | 2/20 | 0.38 |
| ▸ | CCR6 | P51684 | 2/20 | 0.38 |
| ▸ | BLM | P54132 | 2/20 | 0.38 |
| ▸ | UBE2N | P61088 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3030901 | 1.00 | SPHK2 (0.38) | SPHK2SPHK1MEN1KMT2AMAPT | |
| SCHEMBL28510464 | 0.88 | TAS1R3 (0.37) | SPHK2SPHK1MEN1KMT2AMAPT | |
| SCHEMBL9457915 | 0.85 | SPHK2 (0.48) | SPHK2SPHK1MEN1KMT2AMAPT | |
| SCHEMBL9457903 | 0.85 | SPHK2 (0.48) | SPHK2SPHK1MEN1KMT2AMAPT | |
| SCHEMBL9458483 | 0.83 | SPHK2 (0.56) | SPHK2SPHK1MEN1KMT2AMAPT | |
| SCHEMBL9458491 | 0.83 | SPHK2 (0.56) | SPHK2SPHK1MEN1KMT2AMAPT | |
| SCHEMBL11972839 | 0.78 | TSHR (0.33) | MEN1KMT2AALDH1A1CYP3A4TAS1R3 | |
| SCHEMBL7782283 | 0.78 | — | — | |
| SCHEMBL9713123 | 0.78 | TSHR (0.33) | MEN1KMT2AALDH1A1CYP3A4TAS1R3 | |
| SCHEMBL5370849 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8198390-B2 | Self assembled grafted polymeric layer for use in biosensor technology | IMEC (BE) | 2012-06-12 | — | — | US | disclosed |
| US-20100204415-A1 | SELFASSEMBLED GRAFTED POLYMERIC LAYER FOR USE IN BIOSENSOR TECHNOLOGY | IMEC (BE) | 2010-08-12 | — | — | US | disclosed |
| US-7728094-B2 | Selfassembled grafted polymeric layer for use in biosensor technology | IMEC (BE) | 2010-06-01 | — | — | US | disclosed |
| US-20060252094-A1 | Selfassembled grafted polymeric layer for use in biosensor technology | IMEC (BE) | 2006-11-09 | — | — | US | disclosed |
| EP-0559859-B1 | FLUOROBENZONITRILES AND LIQUID CRYSTALLINE MIXTURES CONTAINING THEM | MERCK PATENT GMBH (DE) | 1999-12-08 | — | — | EP | disclosed |
| US-5447658-A | Tricyclic fluorobenzonitrile derivatives | HOFFMAN-LA ROCHE INC. (US) | 1995-09-05 | — | — | US | disclosed |
| US-5238602-A | Electrooptical cells | HOFFMANN LA ROCHE INC. (US) | 1993-08-24 | — | — | US | disclosed |
| US-5013478-A | Electromagnetic radiation resistance; miscibility; dielectrics; rotation and guest/host cells | HOFFMANN-LA ROCHE INC. (US) | 1991-05-07 | — | — | US | disclosed |
| US-4980486-A | Phenyl isothiocyanates | HOFFMANN-LA ROCHE INC. (US) | 1990-12-25 | — | — | US | disclosed |
| EP-0168683-B1 | LIQUID CRYSTALS WITH ALKENYL OR ALKENYLOXY GROUPS | F. HOFFMANN-LA ROCHE AG (CH) | 1990-11-28 | — | — | EP | disclosed |
| US-4915480-A | Liquid crystalline compounds and mixtures | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1990-04-10 | — | — | US | disclosed |
| EP-0172360-B1 | CYCLOHEXANECARBONITRILES AND THEIR USE AS COMPONENTS FOR LIQUID CRYSTALS | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1988-11-09 | — | — | EP | disclosed |
| EP-0169327-B1 | PHENYLISOTHIOCYANATES | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1988-01-13 | — | — | EP | disclosed |
| EP-0122389-B1 | LIQUID CRYSTAL COMPONENTS HAVING AN ALKENYL CHAIN | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1987-08-05 | — | — | EP | disclosed |
| US-4676604-A | RADIATION RESISTANCE; MISCIBILITY; ROTATION ELECTROPTICAL CELLS | HOFFMANN-LA ROCHE INC. (US) | 1987-06-30 | — | — | US | disclosed |
| EP-0172360-A2 | Cyclohexanecarbonitriles and their use as components for liquid crystals | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1986-02-26 | — | — | EP | disclosed |
| EP-0169327-A2 | Phenylisothiocyanates | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1986-01-29 | — | — | EP | disclosed |
| US-4565425-A | Liquid crystals | HOFFMANN-LA ROCHE INC. (US) | 1986-01-21 | — | — | US | disclosed |
| EP-0122389-A2 | Liquid crystal components having an alkenyl chain | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1984-10-24 | — | — | EP | disclosed |