Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SLC34A1 | Q06495 | 3/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.38 |
| ▸ | IGF1R | P08069 | 3/20 | 0.38 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | BCDIN3D | Q7Z5W3 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL171493 | 1.00 | MAPK1 (0.44) | MAPK1HSD11B1MEN1GAAKMT2A | |
| SCHEMBL17200651 | 0.95 | MAPK1 (0.41) | MAPK1HSD11B1MEN1GAAKMT2A | |
| SCHEMBL15155230 | 0.91 | HSD11B1 (0.48) | MAPK1HSD11B1KMT2ASLC34A1TP53 | |
| SCHEMBL29369356 | 0.91 | HSD11B1 (0.48) | MAPK1HSD11B1KMT2ASLC34A1TP53 | |
| SCHEMBL20697907 | 0.90 | HSD11B1 (0.39) | MAPK1HSD11B1MEN1GAAKMT2A | |
| SCHEMBL168717 | 0.90 | HSD11B1 (0.39) | MAPK1HSD11B1MEN1GAAKMT2A | |
| SCHEMBL17200649 | 0.89 | HSD11B1 (0.38) | MAPK1HSD11B1GAASLC34A1P2RX7 | |
| SCHEMBL15155314 | 0.88 | HSD11B1 (0.44) | HSD11B1SLC34A1TP53RXFP1P2RX7 | |
| SCHEMBL20697908 | 0.88 | HSD11B1 (0.39) | MAPK1HSD11B1KMT2ASLC34A1P2RX7 | |
| SCHEMBL29368728 | 0.88 | HSD11B1 (0.44) | HSD11B1SLC34A1TP53RXFP1P2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115955916-A | Active compound combinations | 拜耳公司 | 2023-04-11 | — | — | CN | disclosed |