Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PHF8 | Q9UPP1 | 7/20 | 0.71 |
| ▸ | KDM2A | Q9Y2K7 | 7/20 | 0.71 |
| ▸ | EGLN1 | Q9GZT9 | 5/20 | 0.71 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.71 |
| ▸ | KDM5C | P41229 | 4/20 | 0.71 |
| ▸ | KDM6B | O15054 | 2/20 | 0.71 |
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.52 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.50 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.50 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.48 |
| ▸ | ACE | P12821 | 1/20 | 0.46 |
| ▸ | LDHA | P00338 | 1/20 | 0.42 |
| ▸ | SRR | Q9GZT4 | 1/20 | 0.42 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.42 |
| ▸ | FFAR3 | O14843 | 2/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL218098 | 0.91 | PHF8 (0.65) | PHF8KDM2AEGLN1KDM4EKDM5C | |
| SCHEMBL30572348 | 0.91 | PHF8 (0.65) | PHF8KDM2AEGLN1KDM4EKDM5C | |
| SCHEMBL20377434 | 0.88 | PHF8 (0.62) | PHF8KDM2AEGLN1KDM4EKDM5C | |
| SCHEMBL20377438 | 0.88 | PHF8 (0.62) | PHF8KDM2AEGLN1KDM4EKDM5C | |
| Ammonia Solution, Strong SCHEMBL20377426 | 0.88 | PHF8 (0.62) | PHF8KDM2AEGLN1KDM4EKDM5C | |
| SCHEMBL20377443 | 0.88 | PHF8 (0.62) | PHF8KDM2AEGLN1KDM4EKDM5C | |
| SCHEMBL20377423 | 0.88 | PHF8 (0.62) | PHF8KDM2AEGLN1KDM4EKDM5C | |
| SCHEMBL20377429 | 0.88 | PHF8 (0.62) | PHF8KDM2AEGLN1KDM4EKDM5C | |
| SCHEMBL6914036 | 0.88 | PHF8 (0.62) | PHF8KDM2AEGLN1KDM4EKDM5C | |
| SCHEMBL20377444 | 0.88 | PHF8 (0.62) | PHF8KDM2AEGLN1KDM4EKDM5C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4143325-A1 | FERMENTATIVE PRODUCTION OF BETA-KETOADIPATE FROM GASEOUS SUBSTRATES | Lanzatech, Inc. (US) | 2023-03-08 | — | — | EP | disclosed |