SCHEMBL218098

SCHEMBL218098

O=C(O)CCC(=O)CC(=O)O

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PHF8 Q9UPP1 6/20 0.65
KDM2A Q9Y2K7 6/20 0.65
EGLN1 Q9GZT9 5/20 0.65
KDM4E B2RXH2 4/20 0.65
KDM5C P41229 4/20 0.65
KDM6B O15054 2/20 0.65
LMNA P02545 4/20 0.60
ALKBH5 Q6P6C2 1/20 0.60
SUCNR1 Q9BXA5 1/20 0.60
GABRR1 P24046 1/20 0.55
ACE P12821 1/20 0.52
LDHA P00338 1/20 0.50
SRR Q9GZT4 1/20 0.50
FOLH1 Q04609 1/20 0.48
SLC15A2 Q16348 1/20 0.45
MAPK1 P28482 1/20 0.45
SLC13A3 Q8WWT9 1/20 0.45
OR51E2 Q9H255 1/20 0.45
SLC22A6 Q4U2R8 1/20 0.44
TSHR P16473 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30572348 1.00 PHF8 (0.65) PHF8KDM2AEGLN1KDM4EKDM5C
SCHEMBL20377444 0.97 PHF8 (0.62) PHF8KDM2AEGLN1KDM4EKDM5C
SCHEMBL20377423 0.97 PHF8 (0.62) PHF8KDM2AEGLN1KDM4EKDM5C
SCHEMBL20377434 0.97 PHF8 (0.62) PHF8KDM2AEGLN1KDM4EKDM5C
Ammonia Solution, Strong SCHEMBL20377426 0.97 PHF8 (0.62) PHF8KDM2AEGLN1KDM4EKDM5C
SCHEMBL20377443 0.97 PHF8 (0.62) PHF8KDM2AEGLN1KDM4EKDM5C
SCHEMBL6914036 0.97 PHF8 (0.62) PHF8KDM2AEGLN1KDM4EKDM5C
SCHEMBL20377429 0.97 PHF8 (0.62) PHF8KDM2AEGLN1KDM4EKDM5C
SCHEMBL20377438 0.97 PHF8 (0.62) PHF8KDM2AEGLN1KDM4EKDM5C
Hydrogen Sulfide SCHEMBL28240428 0.97 PHF8 (0.62) PHF8KDM2AEGLN1KDM4EKDM5C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1003 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3346011-B1 HOST CELLS FOR PREPARING ADIPATE (ESTER OR THIOESTER) GENOMATICA INC (US) 2026-05-20 EP claimed
US-12606852-B2 Conversion of lignin-derived monomers to muconate by engineered pseudomonas Alliance for Energy Innovation, LLC (US) 2026-04-21 US claimed
US-20260028651-A1 METHOD OF PRODUCING & PROCESSING DIAMINES AGAIN BIO APS (DK) 2026-01-29 US claimed
US-20260021186-A1 Fatty Acid-D-Amino Acid Peptides Conjugates as Anaplerotic Compounds for Use in Treating Propionic Acidemia, Methylmalonic Acidurias, and Energy Metabolic Disorders UNIV PITTSBURGH COMMONWEALTH SYS HIGHER EDUCATION (US) 2026-01-22 US claimed
US-12503711-B2 Method of producing and processing diamines to a diamine free base using a carbonate intermediate and an engineered microorganism GENOMATICA, INC. (US) 2025-12-23 US claimed
EP-4642908-A2 LIGASE AND DEHYDROGENASE VARIANTS AND METHODS OF USE Genomatica, Inc. (US) 2025-11-05 EP claimed
US-20250215461-A1 GENETICALLY MODIFIED MICROORGANISM FOR PRODUCING 3-HYDROXYADIPIC ACID AND/OR 3-OXOADIPIC ACID, AND PRODUCTION METHOD FOR SAID CHEMICAL PRODUCTS TORAY INDUSTRIES, INC. (JP) 2025-07-03 US claimed
EP-4565325-A2 FATTY ACID-D-AMINO ACID PEPTIDES CONJUGATES AS ANAPLEROTIC COMPOUNDS FOR USE IN TREATING PROPIONIC ACIDEMIA, METHYLMALONIC ACIDURIAS, AND ENERGY METABOLIC DISORDERS UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) 2025-06-11 EP claimed
CN-119855613-A Fatty acid-D-amino acid peptide conjugates as anaplerotic compounds for the treatment of hyperuricemia, methylmalonic urine disorder and energy metabolism disorders 匹兹堡大学高等教育联邦体系 2025-04-18 CN claimed
EP-4497819-A1 GENETICALLY-MODIFIED MICROORGANISM FOR PRODUCING 3-HYDROXYADIPIC ACID AND/OR 3-OXOADIPIC ACID AND PRODUCTION METHOD FOR SAID CHEMICAL PRODUCTS Toray Industries, Inc. (JP) 2025-01-29 EP claimed
US-20060020141-A1 Metallized dye XEROX CORPORATION 2006-01-26 US claimed
US-6989052-B1 Phase change ink printing process XEROX CORPORATION (US) 2006-01-24 US claimed
US-20060004123-A1 PHASE CHANGE INK PRINTING PROCESS XEROX CORPORATION 2006-01-05 US claimed
US-6946025-B2 Process for preparing tetra-amide compounds XEROX CORPORATION (US) 2005-09-20 US claimed
US-20050090690-A1 Process for preparing tetra-amide compounds XEROX CORPORATION 2005-04-28 US claimed
EP-1041154-B1 Process for the preparation of 5-aminolevulinic acid COSMO RES INST (JP) 2003-03-12 EP claimed
EP-1041154-A1 5-Aminolevulinic acid producing microorganism and process for producing 5-aminolevulinic acid COSMO RESEARCH INSTITUTE (JP) 2000-10-04 EP claimed
US-5763235-A PHOTOSYNTHETIC BACTERIUM WHICH PRODUCES 5-AMINOLEVULINIC ACID WITHOUT LIGHT IRRADIATION COSMO RESEARCH INSTITUTE (JP) 1998-06-09 US claimed
EP-0718405-A2 5-Aminolevulinic acid producing microorganism, and process for producing it COSMO RESEARCH INSTITUTE (JP) 1996-06-26 EP claimed
EP-0074169-B1 MICRO-BIOLOGICAL PRODUCTION OF MUCONIC ACID CELANESE CORPORATION (US) 1987-01-14 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250215461-A1 GENETICALLY MODIFIED MICROORGANISM FOR PRODUCING 3-HYDROXYADIPIC ACID AND/OR 3-OXOADIPIC ACID, AND PRODUCTION METHOD FOR SAID CHEMICAL PRODUCTS HMGCR, GNPAT, COASY PHF8 3620/4885KDM2A 3817/4885EGLN1 3294/4885
US-20260028651-A1 METHOD OF PRODUCING & PROCESSING DIAMINES DDC, DAO, ODC1 PHF8 1447/4885KDM2A 1724/4885EGLN1 479/4885
US-20060020141-A1 Metallized dye CDYL, CDY1; CDY1B, CDYL2 PHF8 2309/4885KDM2A 1765/4885EGLN1 4717/4885
US-20260021186-A1 Fatty Acid-D-Amino Acid Peptides Conjugates as Anaplerotic Compounds for Use in Treating Propionic Acidemia, Methylmalonic Acidurias, and Energy Metabolic Disorders HADHB, HADHA, HADH PHF8 2148/4885KDM2A 2091/4885EGLN1 332/4885
US-12606852-B2 Conversion of lignin-derived monomers to muconate by engineered pseudomonas P4HB, COASY, HPD PHF8 545/4885KDM2A 254/4885EGLN1 421/4885
US-20050090690-A1 Process for preparing tetra-amide compounds TAF9, TAF5, TAF1 PHF8 1523/4885KDM2A 1744/4885EGLN1 3980/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.