Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCQ | Q04759 | 15/20 | 0.71 |
| ▸ | ROCK2 | O75116 | 8/20 | 0.71 |
| ▸ | PRKD3 | O94806 | 9/20 | 0.59 |
| ▸ | PRKCG | P05129 | 9/20 | 0.59 |
| ▸ | PRKCZ | Q05513 | 9/20 | 0.59 |
| ▸ | PRKCB | P05771 | 8/20 | 0.59 |
| ▸ | PRKCA | P17252 | 8/20 | 0.59 |
| ▸ | PRKCH | P24723 | 8/20 | 0.59 |
| ▸ | PRKCI | P41743 | 8/20 | 0.59 |
| ▸ | PRKCE | Q02156 | 8/20 | 0.59 |
| ▸ | PRKCD | Q05655 | 8/20 | 0.59 |
| ▸ | PRKD1 | Q15139 | 8/20 | 0.59 |
| ▸ | EGFR | P00533 | 7/20 | 0.59 |
| ▸ | PRKACA | P17612 | 7/20 | 0.59 |
| ▸ | PRKACG | P22612 | 6/20 | 0.59 |
| ▸ | PRKACB | P22694 | 6/20 | 0.59 |
| ▸ | SRC | P12931 | 2/20 | 0.59 |
| ▸ | PKN1 | Q16512 | 1/20 | 0.58 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29447166 | 0.85 | PRKCQ (0.71) | PRKCQROCK2PRKD3PRKCGPRKCZ | |
| SCHEMBL22765174 | 0.84 | PRKCQ (1.00) | PRKCQROCK2PRKD3PRKCGPRKCZ | |
| SCHEMBL1649555 | 0.83 | MAP3K11 (0.67) | PRKCQROCK2PRKD3PRKCGPRKCZ | |
| SCHEMBL29651766 | 0.81 | MAP3K11 (0.80) | PRKCQPRKD3PRKCGPRKCZPRKCB | |
| SCHEMBL14207922 | 0.81 | MAP3K11 (0.80) | PRKCQPRKD3PRKCGPRKCZPRKCB | |
| SCHEMBL20865124 | 0.81 | PRKCQ (0.84) | PRKCQROCK2PRKD3PRKCGPRKCZ | |
| SCHEMBL12963562 | 0.76 | PRKCQ (0.79) | PRKCQROCK2PRKD3PRKCGPRKCZ | |
| SCHEMBL26076886 | 0.76 | PRKCQ (0.85) | PRKCQROCK2PRKD3PRKCGPRKCZ | |
| SCHEMBL24177030 | 0.76 | PRKCQ (0.87) | PRKCQROCK2PRKD3PRKCGPRKCZ | |
| SCHEMBL20841734 | 0.75 | PRKCQ (1.00) | PRKCQROCK2PRKD3PRKCGPRKCZ |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4161582-A2 | ANTIBODY-DRUG CONJUGATES CONTAINING AN ANTI-MESOTHELIN ANTIBODY AND USES THEREOF | Development Center for Biotechnology (TW) | 2023-04-12 | — | — | EP | disclosed |