Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.53 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | GLA | P06280 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | AHR | P35869 | 1/20 | 0.53 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.53 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.53 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.53 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.53 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1144458 | 1.00 | KDM4E (0.53) | KDM4EHSD17B10ALDH1A1HPGDMEN1 | |
| SCHEMBL30396733 | 0.88 | KDM4E (0.50) | KDM4EHSD17B10ALDH1A1HPGDMEN1 | |
| SCHEMBL22394964 | 0.88 | KDM4E (0.50) | KDM4EHSD17B10ALDH1A1HPGDMEN1 | |
| SCHEMBL29425115 | 0.83 | KDM4E (0.51) | KDM4EHSD17B10ALDH1A1HPGDMEN1 | |
| SCHEMBL22395008 | 0.83 | KDM4E (0.51) | KDM4EHSD17B10ALDH1A1HPGDMEN1 | |
| SCHEMBL24190146 | 0.82 | ABL1 (0.46) | KDM4EHSD17B10ALDH1A1HPGDMEN1 | |
| SCHEMBL30396884 | 0.82 | ABL1 (0.46) | KDM4EHSD17B10ALDH1A1HPGDMEN1 | |
| SCHEMBL27379425 | 0.81 | SLC9A1 (0.56) | CYP2C19KIF11AXL | |
| SCHEMBL9452204 | 0.80 | HPGD (0.53) | KDM4EHSD17B10ALDH1A1HPGDMEN1 | |
| Hydrochloric Acid SCHEMBL27447513 | 0.80 | SLC9A1 (0.55) | KDM4EALDH1A1HPGDMEN1CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116096714-A | Antiviral compounds for the treatment of coronavirus, picornavirus and norovirus infections | 安力高医药股份有限公司 | 2023-05-09 | — | — | CN | disclosed |
| EP-4161902-A1 | INHIBITORS OF CYSTEINE PROTEASES AND METHODS OF USE THEREOF | Pardes Biosciences, Inc. (US) | 2023-04-12 | — | — | EP | disclosed |