SCHEMBL30311397

CC(C)[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H]1CCCN1C(=O)[C@H](CCC(=O)O)NC(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)[C@@H]1CCCN1)C(C)C)C(=O)O

nearest known ligand 0.56

Predicted protein targets (top 8)

	gene	UniProt	supporting neighbours	confidence
▸	CALCRL	Q16602	5/20	0.56

▸	MAPK8	P45983	1/20	0.52

▸	MAPK9	P45984	1/20	0.52

▸	MAPK10	P53779	1/20	0.52

▸	RAMP1	O60894	1/20	0.48

▸	REN	P00797	4/20	0.48

▸	EPHA2	P29317	1/20	0.48

▸	KEAP1	Q14145	1/20	0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL30311507	0.93	REN (0.58)	CALCRLMAPK8MAPK9MAPK10REN
SCHEMBL30311212	0.87	REN (0.60)	CALCRLMAPK8MAPK9MAPK10REN
SCHEMBL30311197	0.86	MAPK8 (0.43)	CALCRLMAPK8MAPK9MAPK10REN
SCHEMBL30311096	0.86	REN (0.60)	CALCRLMAPK8MAPK9MAPK10REN
SCHEMBL30051241	0.85	REN (0.55)	CALCRLMAPK8MAPK9MAPK10REN
SCHEMBL30311186	0.85	MAPK8 (0.42)	CALCRLMAPK8MAPK9MAPK10REN
SCHEMBL29580104	0.85	CALCRL (0.56)	CALCRLRAMP1REN
Acetic Acid SCHEMBL30311509	0.84	MAPK8 (0.41)	CALCRLMAPK8MAPK9MAPK10REN
SCHEMBL30311497	0.84	REN (0.48)	CALCRLMAPK8MAPK9MAPK10REN
SCHEMBL30311443	0.83	MAPK8 (0.48)	CALCRLMAPK8MAPK9MAPK10REN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
EP-4177259-A1	POLYPEPTIDE FOR REPAIRING MUCOSAL DAMAGE OR SKIN WOUND AND USE THEREOF	Sichuan Gooddoctor Panxi Pharmaceutical Co. Ltd (CN)	2023-05-10	—	—	EP	disclosed