Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM2B | Q8NHM5 | 16/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | PLG | P00747 | 1/20 | 0.39 |
| ▸ | PLAT | P00750 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.38 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.38 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.38 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21047314 | 0.81 | KDM2B (0.57) | KDM2B | |
| SCHEMBL1421748 | 0.80 | SMN1; SMN2 (0.53) | SMN1; SMN2PLGPLATLMNA | |
| SCHEMBL23855249 | 0.79 | SMN1; SMN2 (0.53) | KDM2BSMN1; SMN2 | |
| SCHEMBL4730783 | 0.79 | SMN1; SMN2 (0.53) | KDM2BSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL28260673 | 0.78 | SMN1; SMN2 (0.51) | SMN1; SMN2PLGPLATLMNA | |
| SCHEMBL19814466 | 0.78 | GABRR1 (0.38) | KDM2BPLGPLATLMNA | |
| SCHEMBL28331096 | 0.78 | GABRR1 (0.38) | KDM2BPLGPLATLMNA | |
| SCHEMBL19814581 | 0.78 | GABRR1 (0.38) | KDM2BPLGPLATLMNA | |
| SCHEMBL4678458 | 0.78 | PLG (0.45) | KDM2BSMN1; SMN2PLGPLATLMNA | |
| SCHEMBL27564353 | 0.76 | KDM2B (0.52) | KDM2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4146660-A1 | BIFUNCTIONAL DEGRADERS OF HEMATOPOIETIC PROGENITOR KINASE AND THERAPEUTIC USES THEREOF | Nurix Therapeutics, Inc. (US) | 2023-03-15 | — | — | EP | disclosed |