Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 1/20 | 0.48 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.48 |
| ▸ | IRAK1 | P51617 | 1/20 | 0.47 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.47 |
| ▸ | CDK1 | P06493 | 10/20 | 0.47 |
| ▸ | CCNB1 | P14635 | 8/20 | 0.47 |
| ▸ | CDK5 | Q00535 | 8/20 | 0.47 |
| ▸ | CDK5R1 | Q15078 | 7/20 | 0.47 |
| ▸ | CCNB2 | O95067 | 6/20 | 0.47 |
| ▸ | CCNB3 | Q8WWL7 | 6/20 | 0.47 |
| ▸ | CDK2 | P24941 | 8/20 | 0.45 |
| ▸ | CCNE1 | P24864 | 5/20 | 0.45 |
| ▸ | CCNA2 | P20248 | 3/20 | 0.45 |
| ▸ | CCNA1 | P78396 | 3/20 | 0.45 |
| ▸ | CCNE2 | O96020 | 2/20 | 0.45 |
| ▸ | CDK9 | P50750 | 3/20 | 0.43 |
| ▸ | CDK4 | P11802 | 4/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.43 |
| ▸ | CDK7 | P50613 | 4/20 | 0.43 |
| ▸ | CCNH | P51946 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2312592 | 1.00 | ADORA2A (0.48) | ADORA2AADORA1IRAK1IRAK4CDK1 | |
| SCHEMBL30315385 | 0.87 | CDK1 (0.45) | CDK1CCNB1CDK5CDK5R1CCNB2 | |
| SCHEMBL2312403 | 0.87 | CDK1 (0.45) | CDK1CCNB1CDK5CDK5R1CCNB2 | |
| SCHEMBL2315254 | 0.81 | CDK2 (0.48) | IRAK4CDK1CCNB1CDK5CDK5R1 | |
| SCHEMBL21017207 | 0.80 | CDK2 (0.52) | CDK1CCNB1CDK5CDK5R1CCNB2 | |
| SCHEMBL3499988 | 0.80 | CDK1 (0.44) | CDK1CCNB1CDK5CDK5R1CCNB2 | |
| SCHEMBL30315450 | 0.80 | CDK1 (0.44) | CDK1CCNB1CDK5CDK5R1CCNB2 | |
| SCHEMBL2313497 | 0.80 | CDK2 (0.52) | CDK1CCNB1CDK5CDK5R1CCNB2 | |
| SCHEMBL2310920 | 0.79 | AHR (0.64) | ADORA2AADORA1IRAK1IRAK4CDK1 | |
| SCHEMBL30315325 | 0.79 | AHR (0.64) | ADORA2AADORA1IRAK1IRAK4CDK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3524604-B1 | EXPANDED HEMATOPOIETIC STEM CELLS FROM CORD BLOOD AND THEIR THERAPEUTIC USE | NOVARTIS AG (CH) | 2023-03-29 | — | — | EP | disclosed |