Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHR | P35869 | 1/20 | 0.70 |
| ▸ | CDK5 | Q00535 | 14/20 | 0.47 |
| ▸ | CDK5R1 | Q15078 | 12/20 | 0.47 |
| ▸ | CDK2 | P24941 | 9/20 | 0.47 |
| ▸ | DYRK1A | Q13627 | 6/20 | 0.47 |
| ▸ | CCNA2 | P20248 | 5/20 | 0.47 |
| ▸ | CCNA1 | P78396 | 5/20 | 0.47 |
| ▸ | CDK1 | P06493 | 13/20 | 0.42 |
| ▸ | CCNB1 | P14635 | 10/20 | 0.42 |
| ▸ | CCNB2 | O95067 | 7/20 | 0.42 |
| ▸ | CCNB3 | Q8WWL7 | 7/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | CDK4 | P11802 | 3/20 | 0.40 |
| ▸ | CCND1 | P24385 | 3/20 | 0.40 |
| ▸ | CCNE1 | P24864 | 3/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.40 |
| ▸ | CDK7 | P50613 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2314146 | 1.00 | AHR (0.70) | AHRCDK5CDK5R1CDK2DYRK1A | |
| SCHEMBL15011335 | 0.85 | AHR (0.87) | AHRCDK5CDK2DYRK1ACCNA2 | |
| SCHEMBL2313531 | 0.84 | AHR (0.71) | AHRCDK5CDK5R1CDK2DYRK1A | |
| SCHEMBL30315451 | 0.84 | AHR (0.71) | AHRCDK5CDK5R1CDK2DYRK1A | |
| SCHEMBL24689885 | 0.83 | AHR (0.72) | AHRCDK5CDK5R1CDK2DYRK1A | |
| SCHEMBL2318576 | 0.83 | AHR (0.69) | AHRCDK5CDK5R1CDK2DYRK1A | |
| SCHEMBL19766270 | 0.83 | AHR (0.85) | AHRCDK5CDK5R1CDK2DYRK1A | |
| SCHEMBL2317306 | 0.83 | AHR (0.85) | AHRCDK5CDK5R1CDK2DYRK1A | |
| SCHEMBL29686381 | 0.82 | AHR (1.00) | AHRCDK5CDK5R1CDK2DYRK1A | |
| SCHEMBL2314090 | 0.82 | AHR (0.79) | AHRCDK5CDK5R1CDK2DYRK1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3524604-B1 | EXPANDED HEMATOPOIETIC STEM CELLS FROM CORD BLOOD AND THEIR THERAPEUTIC USE | NOVARTIS AG (CH) | 2023-03-29 | — | — | EP | disclosed |