Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHR | P35869 | 1/20 | 0.62 |
| ▸ | CDK5 | Q00535 | 10/20 | 0.39 |
| ▸ | CDK1 | P06493 | 10/20 | 0.39 |
| ▸ | CDK5R1 | Q15078 | 8/20 | 0.39 |
| ▸ | CCNB2 | O95067 | 7/20 | 0.39 |
| ▸ | CCNB1 | P14635 | 7/20 | 0.39 |
| ▸ | CCNB3 | Q8WWL7 | 7/20 | 0.39 |
| ▸ | TLR9 | Q9NR96 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | CDK2 | P24941 | 4/20 | 0.36 |
| ▸ | CCNE1 | P24864 | 3/20 | 0.36 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.36 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.36 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.36 |
| ▸ | CLK2 | P49760 | 2/20 | 0.35 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.35 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2314533 | 1.00 | AHR (0.62) | AHRCDK5CDK1CDK5R1CCNB2 | |
| SCHEMBL2310920 | 0.89 | AHR (0.64) | AHRCDK5CDK1CDK5R1CCNB2 | |
| SCHEMBL30315325 | 0.89 | AHR (0.64) | AHRCDK5CDK1CDK5R1CCNB2 | |
| SCHEMBL2312403 | 0.81 | CDK1 (0.45) | CDK5CDK1CDK5R1CCNB2CCNB1 | |
| SCHEMBL30315385 | 0.81 | CDK1 (0.45) | CDK5CDK1CDK5R1CCNB2CCNB1 | |
| SCHEMBL2318576 | 0.81 | AHR (0.69) | AHRCDK5CDK1CDK5R1CCNB2 | |
| SCHEMBL2314146 | 0.80 | AHR (0.70) | AHRCDK5CDK1CDK5R1CCNB2 | |
| SCHEMBL30315381 | 0.80 | AHR (0.70) | AHRCDK5CDK1CDK5R1CCNB2 | |
| SCHEMBL15011335 | 0.79 | AHR (0.87) | AHRCDK5CDK1CCNB2CCNB1 | |
| SCHEMBL24689885 | 0.79 | AHR (0.72) | AHRCDK5CDK1CDK5R1CCNB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3524604-B1 | EXPANDED HEMATOPOIETIC STEM CELLS FROM CORD BLOOD AND THEIR THERAPEUTIC USE | NOVARTIS AG (CH) | 2023-03-29 | — | — | EP | disclosed |