SCHEMBL30316147

SCHEMBL30316147

OCc1ccc(-c2ccccc2-c2nnnn2C(c2ccccc2)(c2ccccc2)c2ccccc2)cc1

nearest known ligand 0.51

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
AGTR1 P30556 1/20 0.51
AGTR2 P50052 1/20 0.51
AGT P01019 2/20 0.39
PTGS2 P35354 1/20 0.38
AKT1 P31749 1/20 0.35
MKNK1 Q9BUB5 1/20 0.35
MKNK2 Q9HBH9 1/20 0.35
KCNN4 O15554 1/20 0.34
TSHR P16473 1/20 0.34
P2RX7 Q99572 2/20 0.34
KIF11 P52732 1/20 0.34
HDAC6 Q9UBN7 1/20 0.33
PDK2 Q15119 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9024777 1.00 AGTR1 (0.51) AGTR1AGTR2AGTPTGS2AKT1
SCHEMBL27586872 0.88 AGTR1 (0.44) AGTR1AGTR2AGTPTGS2P2RX7
SCHEMBL29931122 0.88 AGTR1 (0.44) AGTR1AGTR2AGTPTGS2P2RX7
SCHEMBL13146764 0.88 AGTR1 (0.55) AGTR1AGTR2AGTKCNN4TSHR
SCHEMBL8539585 0.88 AGTR1 (0.52) AGTR1AGTR2AGTAKT1P2RX7
SCHEMBL29404889 0.88 AGTR1 (0.50) AGTR1AGTR2AGTTSHRP2RX7
SCHEMBL8246839 0.88 AGTR1 (0.50) AGTR1AGTR2AGTP2RX7HDAC6
SCHEMBL4246354 0.88 AGTR1 (0.50) AGTR1AGTR2AGTAKT1P2RX7
SCHEMBL796 0.88 AGTR1 (0.50) AGTR1AGTR2AGTTSHRP2RX7
SCHEMBL9307853 0.88 AGTR1 (0.50) AGTR1AGTR2AGTP2RX7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115792063-B Method for detecting related substances of olmesartan medoxomil hydrochlorothiazide tablets 珠海润都制药股份有限公司 2025-04-04 CN claimed
CN-115792063-B Method for detecting related substances of olmesartan medoxomil hydrochlorothiazide tablets 珠海润都制药股份有限公司 2025-04-04 CN disclosed
CN-118546100-B Method for synthesizing tetrazole by recovering triphenylmethyl ether in alisartan ester waste residues 山东信立泰药业有限公司 2024-09-27 CN disclosed
CN-118546100-A Method for synthesizing tetrazole by recovering triphenylmethyl ether in alisartan ester waste residues 山东信立泰药业有限公司 2024-08-27 CN disclosed
CN-116813552-A Recovery and purification process of olmesartan intermediate impurities 江苏阿尔法药业股份有限公司 2023-09-29 CN disclosed
CN-115792063-A Method for detecting related substances of olmesartan medoxomil hydrochlorothiazide tablets 珠海润都制药股份有限公司 2023-03-14 CN disclosed