Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM4 | Q14833 | 2/20 | 0.31 |
| ▸ | SGK1 | O00141 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25204873 | 1.00 | GRM4 (0.31) | GRM4SGK1 | |
| SCHEMBL25208146 | 0.80 | GRM4 (0.33) | GRM4 | |
| SCHEMBL30849114 | 0.80 | GRM4 (0.33) | GRM4 | |
| SCHEMBL24283777 | 0.77 | GRM4 (0.31) | GRM4 | |
| SCHEMBL29490926 | 0.77 | GRM4 (0.31) | GRM4 | |
| SCHEMBL30424529 | 0.77 | GRM4 (0.31) | GRM4 | |
| SCHEMBL23169547 | 0.77 | ALDH1A1 (0.37) | GRM4SGK1 | |
| SCHEMBL30328027 | 0.77 | GRM4 (0.31) | GRM4 | |
| SCHEMBL23064021 | 0.72 | HCAR2 (0.40) | — | |
| SCHEMBL23443035 | 0.69 | MAPK1 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4363423-A1 | CDK2 INHIBITORS | Blueprint Medicines Corporation (US) | 2024-05-08 | — | — | EP | disclosed |
| WO-2023278326-A1 | CDK2 INHIBITORS | BLUEPRINT MEDICINES CORPORATION (US) | 2023-01-05 | — | — | WO | disclosed |