Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.54 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.51 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.51 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.51 |
| ▸ | HTR1A | P08908 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.51 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.51 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | TRPM2 | O94759 | 1/20 | 0.43 |
| ▸ | PARP1 | P09874 | 1/20 | 0.43 |
| ▸ | HTR1B | P28222 | 1/20 | 0.41 |
| ▸ | LTB4R | Q15722 | 3/20 | 0.39 |
| ▸ | LTB4R2 | Q9NPC1 | 3/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28986027 | 1.00 | MRGPRX4 (0.54) | MRGPRX4ADRB2ADRB1ADRB3HTR1A | |
| SCHEMBL13481244 | 0.85 | MRGPRX4 (0.54) | MRGPRX4ADRB2ADRB1ADRB3HTR1A | |
| SCHEMBL11806193 | 0.84 | MRGPRX4 (0.53) | MRGPRX4ADRB2ADRB1ADRB3HTR1A | |
| SCHEMBL5353946 | 0.82 | MRGPRX4 (0.52) | MRGPRX4ADRB2ADRB1ADRB3HTR1A | |
| SCHEMBL5270656 | 0.81 | MRGPRX4 (0.56) | MRGPRX4ADRB2ADRB1ADRB3HTR1A | |
| SCHEMBL28985965 | 0.79 | RAB9A (0.60) | MRGPRX4ADRB2ADRB1ADRB3HTR1A | |
| SCHEMBL30317440 | 0.79 | RAB9A (0.60) | MRGPRX4ADRB2ADRB1ADRB3HTR1A | |
| SCHEMBL11127019 | 0.79 | ABCB1 (0.53) | MRGPRX4ADRB2ADRB1ADRB3HTR1A | |
| SCHEMBL21821534 | 0.79 | MRGPRX4 (0.54) | MRGPRX4ADRB2ADRB1ADRB3HTR1A | |
| SCHEMBL10606673 | 0.78 | RAB9A (0.52) | MRGPRX4ADRB2ADRB1ADRB3HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115960032-A | Aryloxy propanol amine beta-adrenaline receptor ligand with beta-arrestin biased agonistic activity and application thereof | 复旦大学 | 2023-04-14 | — | — | CN | disclosed |